Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity
Highlights Most secondary metabolites tentatively identified in H. brasiletto are homoisoflavones. Hidroalcoholic extract of H. brasiletto protects C. elegans from Cd toxicity The extract diminished Cd-induced damage to reproduction, growth, and locomotion. Cd-induced oxidative stress and translocat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-07-01
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| Series: | BMC Complementary Medicine and Therapies |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12906-022-03654-6 |
| _version_ | 1818517660138209280 |
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| author | Margareth Duran-Izquierdo María Taboada-Alquerque Lucellys Sierra-Marquez Neda Alvarez-Ortega Elena Stashenko Jesus Olivero-Verbel |
| author_facet | Margareth Duran-Izquierdo María Taboada-Alquerque Lucellys Sierra-Marquez Neda Alvarez-Ortega Elena Stashenko Jesus Olivero-Verbel |
| author_sort | Margareth Duran-Izquierdo |
| collection | DOAJ |
| description | Highlights Most secondary metabolites tentatively identified in H. brasiletto are homoisoflavones. Hidroalcoholic extract of H. brasiletto protects C. elegans from Cd toxicity The extract diminished Cd-induced damage to reproduction, growth, and locomotion. Cd-induced oxidative stress and translocation of DAF-16 are blocked by the extract. |
| first_indexed | 2024-12-11T00:59:17Z |
| format | Article |
| id | doaj.art-c1469d2e86ae4e11a5a7869383333c4c |
| institution | Directory Open Access Journal |
| issn | 2662-7671 |
| language | English |
| last_indexed | 2024-12-11T00:59:17Z |
| publishDate | 2022-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary Medicine and Therapies |
| spelling | doaj.art-c1469d2e86ae4e11a5a7869383333c4c2022-12-22T01:26:22ZengBMCBMC Complementary Medicine and Therapies2662-76712022-07-0122111010.1186/s12906-022-03654-6Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicityMargareth Duran-Izquierdo0María Taboada-Alquerque1Lucellys Sierra-Marquez2Neda Alvarez-Ortega3Elena Stashenko4Jesus Olivero-Verbel5Environmental and Computational Chemistry Group, School of Pharmaceutical Sciences, Zaragocilla Campus, University of CartagenaEnvironmental and Computational Chemistry Group, School of Pharmaceutical Sciences, Zaragocilla Campus, University of CartagenaEnvironmental and Computational Chemistry Group, School of Pharmaceutical Sciences, Zaragocilla Campus, University of CartagenaEnvironmental and Computational Chemistry Group, School of Pharmaceutical Sciences, Zaragocilla Campus, University of CartagenaCenter for Chromatography and Mass Spectrometry, CROM-MASS, CIBIMOL-CENIVAM, Industrial University of SantanderEnvironmental and Computational Chemistry Group, School of Pharmaceutical Sciences, Zaragocilla Campus, University of CartagenaHighlights Most secondary metabolites tentatively identified in H. brasiletto are homoisoflavones. Hidroalcoholic extract of H. brasiletto protects C. elegans from Cd toxicity The extract diminished Cd-induced damage to reproduction, growth, and locomotion. Cd-induced oxidative stress and translocation of DAF-16 are blocked by the extract.https://doi.org/10.1186/s12906-022-03654-6NematodeOxidative stressFabaceaeDaf-16Biodiversity |
| spellingShingle | Margareth Duran-Izquierdo María Taboada-Alquerque Lucellys Sierra-Marquez Neda Alvarez-Ortega Elena Stashenko Jesus Olivero-Verbel Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity BMC Complementary Medicine and Therapies Nematode Oxidative stress Fabaceae Daf-16 Biodiversity |
| title | Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity |
| title_full | Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity |
| title_fullStr | Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity |
| title_full_unstemmed | Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity |
| title_short | Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity |
| title_sort | hydroalcoholic extract of haematoxylum brasiletto protects caenorhabditis elegans from cadmium induced toxicity |
| topic | Nematode Oxidative stress Fabaceae Daf-16 Biodiversity |
| url | https://doi.org/10.1186/s12906-022-03654-6 |
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