Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register
<p>Debridement, antibiotics, and implant retention (DAIR) is a procedure to treat a periprosthetic joint infection (PJI) after total hip arthroplasty (THA) or total knee arthroplasty (TKA). The timing between the primary procedure and the DAIR is likely a determinant for its successful outcome...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Copernicus Publications
2021-09-01
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| Series: | Journal of Bone and Joint Infection |
| Online Access: | https://jbji.copernicus.org/articles/6/329/2021/jbji-6-329-2021.pdf |
| _version_ | 1829518231547674624 |
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| author | B. van der Ende J. van Oldenrijk M. Reijman P. D. Croughs L. N. van Steenbergen J. A. N. Verhaar P. K. Bos |
| author_facet | B. van der Ende J. van Oldenrijk M. Reijman P. D. Croughs L. N. van Steenbergen J. A. N. Verhaar P. K. Bos |
| author_sort | B. van der Ende |
| collection | DOAJ |
| description | <p>Debridement, antibiotics, and implant retention (DAIR) is a procedure to treat a periprosthetic joint infection (PJI) after total hip arthroplasty (THA) or total knee arthroplasty (TKA). The timing between the primary procedure and the DAIR is likely a determinant for its successful outcome. However, the
optimal timing of a DAIR and the chance of success still remain unclear. We aimed to assess the risk of re-revision within 1 year after a DAIR
procedure and to evaluate the timing of the DAIR in primary THA and TKA. We
used data from the Dutch Arthroplasty Register (LROI) and selected all
primary THA and TKA in the period 2007–2016 which underwent a DAIR within 12 weeks after primary procedure. A DAIR was defined as a revision for
infection in which only modular parts were exchanged. A DAIR was defined as successful if not followed by a re-revision within 1 year after DAIR; 207
DAIRs were performed <span class="inline-formula"><4</span> weeks after THA, of which 16 (8 %) received a complete revision within 1 year. DAIR procedures performed between 4 and 12 weeks (<span class="inline-formula"><i>n</i>=98</span>) had a failure rate of 9 % (<span class="inline-formula"><i>n</i>=9</span>). After TKA 126 DAIRs were
performed in less than <span class="inline-formula">4</span> weeks, of which 11 (9 %) received a complete revision within 1 year; 83 DAIRs were performed between 4 and 12 weeks, of which 14 (17 %) were revised.</p>
<p>There was no significant difference in 1-year re-revision rate after a DAIR
procedure by timing of the DAIR procedure for total hip and knee arthroplasty based on Dutch registry data.</p> |
| first_indexed | 2024-12-16T14:16:05Z |
| format | Article |
| id | doaj.art-c15488cfee5d4986a455305bf9de9ebe |
| institution | Directory Open Access Journal |
| issn | 2206-3552 |
| language | English |
| last_indexed | 2024-12-16T14:16:05Z |
| publishDate | 2021-09-01 |
| publisher | Copernicus Publications |
| record_format | Article |
| series | Journal of Bone and Joint Infection |
| spelling | doaj.art-c15488cfee5d4986a455305bf9de9ebe2022-12-21T22:28:36ZengCopernicus PublicationsJournal of Bone and Joint Infection2206-35522021-09-01632933610.5194/jbji-6-329-2021Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty RegisterB. van der Ende0J. van Oldenrijk1M. Reijman2P. D. Croughs3L. N. van Steenbergen4J. A. N. Verhaar5P. K. Bos6Department of Orthopaedic Surgery and Sport Medicine, Erasmus University Medical Center, Rotterdam, 3000 CA, the NetherlandsDepartment of Orthopaedic Surgery and Sport Medicine, Erasmus University Medical Center, Rotterdam, 3000 CA, the NetherlandsDepartment of Orthopaedic Surgery and Sport Medicine, Erasmus University Medical Center, Rotterdam, 3000 CA, the NetherlandsDepartment of Microbiology, Erasmus University Medical Center, Rotterdam, 3000 CA, the NetherlandsDutch Arthroplasty Register (Landelijke Registratie Orthopedische Implantaten), 's Hertogenbosch, 5232 AD, the NetherlandsDepartment of Orthopaedic Surgery and Sport Medicine, Erasmus University Medical Center, Rotterdam, 3000 CA, the NetherlandsDepartment of Orthopaedic Surgery and Sport Medicine, Erasmus University Medical Center, Rotterdam, 3000 CA, the Netherlands<p>Debridement, antibiotics, and implant retention (DAIR) is a procedure to treat a periprosthetic joint infection (PJI) after total hip arthroplasty (THA) or total knee arthroplasty (TKA). The timing between the primary procedure and the DAIR is likely a determinant for its successful outcome. However, the optimal timing of a DAIR and the chance of success still remain unclear. We aimed to assess the risk of re-revision within 1 year after a DAIR procedure and to evaluate the timing of the DAIR in primary THA and TKA. We used data from the Dutch Arthroplasty Register (LROI) and selected all primary THA and TKA in the period 2007–2016 which underwent a DAIR within 12 weeks after primary procedure. A DAIR was defined as a revision for infection in which only modular parts were exchanged. A DAIR was defined as successful if not followed by a re-revision within 1 year after DAIR; 207 DAIRs were performed <span class="inline-formula"><4</span> weeks after THA, of which 16 (8 %) received a complete revision within 1 year. DAIR procedures performed between 4 and 12 weeks (<span class="inline-formula"><i>n</i>=98</span>) had a failure rate of 9 % (<span class="inline-formula"><i>n</i>=9</span>). After TKA 126 DAIRs were performed in less than <span class="inline-formula">4</span> weeks, of which 11 (9 %) received a complete revision within 1 year; 83 DAIRs were performed between 4 and 12 weeks, of which 14 (17 %) were revised.</p> <p>There was no significant difference in 1-year re-revision rate after a DAIR procedure by timing of the DAIR procedure for total hip and knee arthroplasty based on Dutch registry data.</p>https://jbji.copernicus.org/articles/6/329/2021/jbji-6-329-2021.pdf |
| spellingShingle | B. van der Ende J. van Oldenrijk M. Reijman P. D. Croughs L. N. van Steenbergen J. A. N. Verhaar P. K. Bos Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register Journal of Bone and Joint Infection |
| title | Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register |
| title_full | Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register |
| title_fullStr | Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register |
| title_full_unstemmed | Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register |
| title_short | Timing of debridement, antibiotics, and implant retention (DAIR) for early post-surgical hip and knee prosthetic joint infection (PJI) does not affect 1-year re-revision rates: data from the Dutch Arthroplasty Register |
| title_sort | timing of debridement antibiotics and implant retention dair for early post surgical hip and knee prosthetic joint infection pji does not affect 1 year re revision rates data from the dutch arthroplasty register |
| url | https://jbji.copernicus.org/articles/6/329/2021/jbji-6-329-2021.pdf |
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