Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia
Background. Persistent elevation in beta-human chorionic gonadotropin (β-hCG) following a pregnancy is concerning for gestational trophoblastic neoplasia (GTN). However, the differential diagnosis should remain broad during the evaluation process. Case. A 34-year-old G3P3 presented with elevated β-h...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2023/1901858 |
| _version_ | 1797903056330817536 |
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| author | Conner Blackwell Shian McLeish David Iglesias Shannon D. Armbruster |
| author_facet | Conner Blackwell Shian McLeish David Iglesias Shannon D. Armbruster |
| author_sort | Conner Blackwell |
| collection | DOAJ |
| description | Background. Persistent elevation in beta-human chorionic gonadotropin (β-hCG) following a pregnancy is concerning for gestational trophoblastic neoplasia (GTN). However, the differential diagnosis should remain broad during the evaluation process. Case. A 34-year-old G3P3 presented with elevated β-hCG four months after cesarean delivery with bilateral tubal ligation. The patient was treated with methotrexate for a presumed new ectopic pregnancy. Due to persistent β-hCG elevation, she received actinomycin-D for GTN treatment. After completing chemotherapy, her β-hCG increased. The patient underwent a laparoscopic hysterectomy with unplanned left oophorectomy due to its nodular appearance at the time of surgery. Pathology confirmed a dysgerminoma of the ovary and benign uterus. Conclusion. Although dysgerminomas are uncommon, they should be considered when β-hCG levels remain elevated despite therapies for more common pathologies. |
| first_indexed | 2024-04-10T09:26:57Z |
| format | Article |
| id | doaj.art-c154e5257f5d475599346607674fe19f |
| institution | Directory Open Access Journal |
| issn | 2090-6692 |
| language | English |
| last_indexed | 2024-04-10T09:26:57Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj.art-c154e5257f5d475599346607674fe19f2023-02-20T01:58:08ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66922023-01-01202310.1155/2023/1901858Dysgerminoma Masquerading as Gestational Trophoblastic NeoplasiaConner Blackwell0Shian McLeish1David Iglesias2Shannon D. Armbruster3Department of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyBackground. Persistent elevation in beta-human chorionic gonadotropin (β-hCG) following a pregnancy is concerning for gestational trophoblastic neoplasia (GTN). However, the differential diagnosis should remain broad during the evaluation process. Case. A 34-year-old G3P3 presented with elevated β-hCG four months after cesarean delivery with bilateral tubal ligation. The patient was treated with methotrexate for a presumed new ectopic pregnancy. Due to persistent β-hCG elevation, she received actinomycin-D for GTN treatment. After completing chemotherapy, her β-hCG increased. The patient underwent a laparoscopic hysterectomy with unplanned left oophorectomy due to its nodular appearance at the time of surgery. Pathology confirmed a dysgerminoma of the ovary and benign uterus. Conclusion. Although dysgerminomas are uncommon, they should be considered when β-hCG levels remain elevated despite therapies for more common pathologies.http://dx.doi.org/10.1155/2023/1901858 |
| spellingShingle | Conner Blackwell Shian McLeish David Iglesias Shannon D. Armbruster Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia Case Reports in Obstetrics and Gynecology |
| title | Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia |
| title_full | Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia |
| title_fullStr | Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia |
| title_full_unstemmed | Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia |
| title_short | Dysgerminoma Masquerading as Gestational Trophoblastic Neoplasia |
| title_sort | dysgerminoma masquerading as gestational trophoblastic neoplasia |
| url | http://dx.doi.org/10.1155/2023/1901858 |
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