CRISPRi gene modulation and all-optical electrophysiology in post-differentiated human iPSC-cardiomyocytes
Abstract Uncovering gene-phenotype relationships can be enabled by precise gene modulation in human induced pluripotent stem-cell-derived cardiomyocytes (iPSC-CMs) and follow up phenotyping using scalable all-optical electrophysiology platforms. Such efforts towards human functional genomics can be...
Những tác giả chính: | , , , , |
---|---|
Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
Nature Portfolio
2023-12-01
|
Loạt: | Communications Biology |
Truy cập trực tuyến: | https://doi.org/10.1038/s42003-023-05627-y |