CRISPRi gene modulation and all-optical electrophysiology in post-differentiated human iPSC-cardiomyocytes

CRISPRi gene modulation and all-optical electrophysiology in post-differentiated human iPSC-cardiomyocytes

Abstract Uncovering gene-phenotype relationships can be enabled by precise gene modulation in human induced pluripotent stem-cell-derived cardiomyocytes (iPSC-CMs) and follow up phenotyping using scalable all-optical electrophysiology platforms. Such efforts towards human functional genomics can be...

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Bibliographic Details
Main Authors:	Julie L. Han, Yuli W. Heinson, Christianne J. Chua, Wei Liu, Emilia Entcheva
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-023-05627-y

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