Synthesis of Proposed Structure of Aaptoline B via Transition Metal-Catalyzed Cycloisomerization and Evaluation of Its Neuroprotective Properties in <i>C. Elegans</i>

A concise synthesis of the proposed structure of aaptoline B, a pyrroloquinoline derived from a marine sponge, was accomplished. A key feature of this synthesis is the versatile transition metal-catalyzed cycloisomerization of <i>N</i>-propargylaniline to construct a quinoline skeleton....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Soobin Kim, Wooin Yang, Young-Taek Han, Dong-Seok Cha
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2021-09-01
Цуврал:Applied Sciences
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/2076-3417/11/19/9125