Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
Functional microcirculatory abnormalities in the foot have been given much attention in the recent years for their potential pathogenetic role in thedevelopment of diabetic neuropathy and diabetic foot syndrome. This paper reviews data on the disturbances of skin microcirculation in lower extremitie...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2011-09-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/6224 |
| _version_ | 1797255304789884928 |
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| author | Vadim Borisovich Bregovsky I A Karpova E S Alekseeva |
| author_facet | Vadim Borisovich Bregovsky I A Karpova E S Alekseeva |
| author_sort | Vadim Borisovich Bregovsky |
| collection | DOAJ |
| description | Functional microcirculatory abnormalities in the foot have been given much attention in the recent years for their potential pathogenetic role in thedevelopment of diabetic neuropathy and diabetic foot syndrome. This paper reviews data on the disturbances of skin microcirculation in lower extremitieswith reference to the role of neuropathy and endothelial dysfunction in this pathology. Possible relationships between end-stage renal disease, highplantar pressure and compromised skin microcirculation are discussed. The influence of several drugs on foot skin microcirculation and prospects fortheir use for therapeutic purposes are considered. |
| first_indexed | 2024-03-08T15:21:42Z |
| format | Article |
| id | doaj.art-c15df8df8cb24d5783b7ca419ae9512d |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:03:44Z |
| publishDate | 2011-09-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-c15df8df8cb24d5783b7ca419ae9512d2024-03-20T11:47:57ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782011-09-01143495310.14341/2072-0351-62246182Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?Vadim Borisovich Bregovsky0I A Karpova1E S Alekseeva2Sankt-Peterburg Territorial Diabetological Centre, Sankt-PeterburgSankt-Peterburg Territorial Diabetological Centre, Sankt-PeterburgFederal Centre of Heart, Blood and Endocrinology, Sankt-PeterburgFunctional microcirculatory abnormalities in the foot have been given much attention in the recent years for their potential pathogenetic role in thedevelopment of diabetic neuropathy and diabetic foot syndrome. This paper reviews data on the disturbances of skin microcirculation in lower extremitieswith reference to the role of neuropathy and endothelial dysfunction in this pathology. Possible relationships between end-stage renal disease, highplantar pressure and compromised skin microcirculation are discussed. The influence of several drugs on foot skin microcirculation and prospects fortheir use for therapeutic purposes are considered.https://www.dia-endojournals.ru/jour/article/view/6224diabetes mellitusmicroangiopathymicrocirculationpolyneuropathy |
| spellingShingle | Vadim Borisovich Bregovsky I A Karpova E S Alekseeva Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy? Сахарный диабет diabetes mellitus microangiopathy microcirculation polyneuropathy |
| title | Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy? |
| title_full | Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy? |
| title_fullStr | Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy? |
| title_full_unstemmed | Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy? |
| title_short | Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy? |
| title_sort | disturbances of skin microcirculation in lower extremities in diabetes mellitus a pathophysiological phenomenon or an object for therapy |
| topic | diabetes mellitus microangiopathy microcirculation polyneuropathy |
| url | https://www.dia-endojournals.ru/jour/article/view/6224 |
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