Development, In-Vitro Characterization and In-Vivo Osteoinductive Efficacy of a Novel Biomimetically-Precipitated Nanocrystalline Calcium Phosphate With Internally-Incorporated Bone Morphogenetic Protein-2

Development, In-Vitro Characterization and In-Vivo Osteoinductive Efficacy of a Novel Biomimetically-Precipitated Nanocrystalline Calcium Phosphate With Internally-Incorporated Bone Morphogenetic Protein-2

The repair of large-volume bone defects (LVBDs) remains a great challenge in the fields of orthopedics and maxillofacial surgery. Most clinically available bone-defect-filling materials lack proper degradability and efficient osteoinductivity. In this study, we synthesized a novel biomimetically-pre...

Full description

Bibliographic Details
Main Authors: Gaoli Xu, Chenxi Shen, Haiyan Lin, Jian Zhou, Ting Wang, Ben Wan, Munerah Binshabaib, Tymour Forouzanfar, Guochao Xu, Nawal Alharbi, Gang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
nanocrystalline
hydroxyapatite
bone morphogenetic protein-2
biomimetic
bone regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.920696/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.920696/full

Similar Items