Quantum Inspired Genetic Algorithm for Double Digest Problem

The double digest problem (DDP) is a fundamental problem in bioinformatics, and it has been proven to be an NP-hard problem. As a type of promising combinational optimization method inspired by evolutionary theory, genetic algorithms have attracted much attention during the past four decades, and so...

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Main Authors: Jingwen Suo, Lize Gu, Yun Pan, Sijia Yang, Xiaoya Hu
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9068928/
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author Jingwen Suo
Lize Gu
Yun Pan
Sijia Yang
Xiaoya Hu
author_facet Jingwen Suo
Lize Gu
Yun Pan
Sijia Yang
Xiaoya Hu
author_sort Jingwen Suo
collection DOAJ
description The double digest problem (DDP) is a fundamental problem in bioinformatics, and it has been proven to be an NP-hard problem. As a type of promising combinational optimization method inspired by evolutionary theory, genetic algorithms have attracted much attention during the past four decades, and some genetic algorithms have been successfully applied to solve the DDP. To further enhance the ability to solve the DDP, it is of interest to couple the insights from classical genetic algorithms with the parallel capability of quantum computation. Thus, in this paper, we propose a quantum inspired genetic algorithm (QIGA) for the DDP. In our QIGA, the binary Q-bit representation is converted to mapping sequences, and on this basis, DNA fragments are reordered. The solution of the DDP is a permutation, selected by the QIGA, of all the DNA fragments. The effectiveness and efficiency of our proposal can be inferred from the simulation results for the QIGA on a classical computer. As far as we know, this is the first attempt to address the DDP using a QIGA. Compared with classical genetic algorithms for the DDP, our QIGA slightly accelerates the time require to solve the problem, and we believe that it will achieve superior performance when a quantum computer with the required scale is available.
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spelling doaj.art-c161a956084c4ae6b567be8eb7c3dc152022-12-21T22:01:39ZengIEEEIEEE Access2169-35362020-01-018729107291610.1109/ACCESS.2020.29881179068928Quantum Inspired Genetic Algorithm for Double Digest ProblemJingwen Suo0https://orcid.org/0000-0001-5744-9296Lize Gu1Yun Pan2Sijia Yang3Xiaoya Hu4State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing, ChinaState Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing, ChinaSchool of Computer Sciences and Technology, Communication University of China, Beijing, ChinaState Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing, ChinaState Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing, ChinaThe double digest problem (DDP) is a fundamental problem in bioinformatics, and it has been proven to be an NP-hard problem. As a type of promising combinational optimization method inspired by evolutionary theory, genetic algorithms have attracted much attention during the past four decades, and some genetic algorithms have been successfully applied to solve the DDP. To further enhance the ability to solve the DDP, it is of interest to couple the insights from classical genetic algorithms with the parallel capability of quantum computation. Thus, in this paper, we propose a quantum inspired genetic algorithm (QIGA) for the DDP. In our QIGA, the binary Q-bit representation is converted to mapping sequences, and on this basis, DNA fragments are reordered. The solution of the DDP is a permutation, selected by the QIGA, of all the DNA fragments. The effectiveness and efficiency of our proposal can be inferred from the simulation results for the QIGA on a classical computer. As far as we know, this is the first attempt to address the DDP using a QIGA. Compared with classical genetic algorithms for the DDP, our QIGA slightly accelerates the time require to solve the problem, and we believe that it will achieve superior performance when a quantum computer with the required scale is available.https://ieeexplore.ieee.org/document/9068928/Double digest problemquantum inspired genetic algorithmDNA mapping
spellingShingle Jingwen Suo
Lize Gu
Yun Pan
Sijia Yang
Xiaoya Hu
Quantum Inspired Genetic Algorithm for Double Digest Problem
IEEE Access
Double digest problem
quantum inspired genetic algorithm
DNA mapping
title Quantum Inspired Genetic Algorithm for Double Digest Problem
title_full Quantum Inspired Genetic Algorithm for Double Digest Problem
title_fullStr Quantum Inspired Genetic Algorithm for Double Digest Problem
title_full_unstemmed Quantum Inspired Genetic Algorithm for Double Digest Problem
title_short Quantum Inspired Genetic Algorithm for Double Digest Problem
title_sort quantum inspired genetic algorithm for double digest problem
topic Double digest problem
quantum inspired genetic algorithm
DNA mapping
url https://ieeexplore.ieee.org/document/9068928/
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AT lizegu quantuminspiredgeneticalgorithmfordoubledigestproblem
AT yunpan quantuminspiredgeneticalgorithmfordoubledigestproblem
AT sijiayang quantuminspiredgeneticalgorithmfordoubledigestproblem
AT xiaoyahu quantuminspiredgeneticalgorithmfordoubledigestproblem