Immunization With a Live-Attenuated RH:ΔNPT1 Strain of Toxoplasma gondii Induces Strong Protective Immunity Against Toxoplasmosis in Mice

Immunization With a Live-Attenuated RH:ΔNPT1 Strain of Toxoplasma gondii Induces Strong Protective Immunity Against Toxoplasmosis in Mice

Toxoplasmosis, one of the most important health-threatening diseases worldwide, is caused by Toxoplasma gondii, which infects a wide range of warm-blooded animals and humans, leading to enormous health and socioeconomic concerns. T. gondii can establish chronic infection to evade the immune response...

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Bibliographic Details
Main Authors: Wen-Bin Yang, Jin-Lei Wang, Qian Gui, Yang Zou, Kai Chen, Qing Liu, Qin-Li Liang, Xing-Quan Zhu, Dong-Hui Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Toxoplasma gondii
RH:ΔNPT1
immunization
live-attenuated vaccine
mice
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01875/full

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