Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies
Abstract Genetic modification of living organisms has been a prosperous activity for research and development of agricultural, industrial and biomedical applications. Three decades have passed since the first genetically modified products, obtained by transgenesis, become available to the market. Th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | Biological Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40659-022-00399-x |
| _version_ | 1798028552012038144 |
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| author | Pablo Rozas Eduardo I. Kessi-Pérez Claudio Martínez |
| author_facet | Pablo Rozas Eduardo I. Kessi-Pérez Claudio Martínez |
| author_sort | Pablo Rozas |
| collection | DOAJ |
| description | Abstract Genetic modification of living organisms has been a prosperous activity for research and development of agricultural, industrial and biomedical applications. Three decades have passed since the first genetically modified products, obtained by transgenesis, become available to the market. The regulatory frameworks across the world have not been able to keep up to date with new technologies, monitoring and safety concerns. New genome editing techniques are opening new avenues to genetic modification development and uses, putting pressure on these frameworks. Here we discuss the implications of definitions of living/genetically modified organisms, the evolving genome editing tools to obtain them and how the regulatory frameworks around the world have taken these technologies into account, with a focus on agricultural crops. Finally, we expand this review beyond commercial crops to address living modified organism uses in food industry, biomedical applications and climate change-oriented solutions. |
| first_indexed | 2024-04-11T19:10:10Z |
| format | Article |
| id | doaj.art-c1671528ca024d8fa937504f89c3790f |
| institution | Directory Open Access Journal |
| issn | 0717-6287 |
| language | English |
| last_indexed | 2024-04-11T19:10:10Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Biological Research |
| spelling | doaj.art-c1671528ca024d8fa937504f89c3790f2022-12-22T04:07:39ZengBMCBiological Research0717-62872022-10-0155111410.1186/s40659-022-00399-xGenetically modified organisms: adapting regulatory frameworks for evolving genome editing technologiesPablo Rozas0Eduardo I. Kessi-Pérez1Claudio Martínez2Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de ChileCentro de Estudios en Ciencia y Tecnología de Alimentos (CECTA), Universidad de Santiago de Chile (USACH)Centro de Estudios en Ciencia y Tecnología de Alimentos (CECTA), Universidad de Santiago de Chile (USACH)Abstract Genetic modification of living organisms has been a prosperous activity for research and development of agricultural, industrial and biomedical applications. Three decades have passed since the first genetically modified products, obtained by transgenesis, become available to the market. The regulatory frameworks across the world have not been able to keep up to date with new technologies, monitoring and safety concerns. New genome editing techniques are opening new avenues to genetic modification development and uses, putting pressure on these frameworks. Here we discuss the implications of definitions of living/genetically modified organisms, the evolving genome editing tools to obtain them and how the regulatory frameworks around the world have taken these technologies into account, with a focus on agricultural crops. Finally, we expand this review beyond commercial crops to address living modified organism uses in food industry, biomedical applications and climate change-oriented solutions.https://doi.org/10.1186/s40659-022-00399-xBiomedicineClimate changeFoodGenetically modified organism (GMO)New breeding techniques (NBT)Regulatory frameworks |
| spellingShingle | Pablo Rozas Eduardo I. Kessi-Pérez Claudio Martínez Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies Biological Research Biomedicine Climate change Food Genetically modified organism (GMO) New breeding techniques (NBT) Regulatory frameworks |
| title | Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies |
| title_full | Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies |
| title_fullStr | Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies |
| title_full_unstemmed | Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies |
| title_short | Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies |
| title_sort | genetically modified organisms adapting regulatory frameworks for evolving genome editing technologies |
| topic | Biomedicine Climate change Food Genetically modified organism (GMO) New breeding techniques (NBT) Regulatory frameworks |
| url | https://doi.org/10.1186/s40659-022-00399-x |
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