Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization
Purpose: To report the case of a patient with unilateral idiopathic macular telangiectasia (IMT) associated with type 3 neovascularization. Methods: Observational case report. Results: We describe a case of an 85-year-old woman who presented at our department with a gradual vision loss in her left e...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2014-11-01
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| Series: | Case Reports in Ophthalmology |
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| Online Access: | http://www.karger.com/Article/FullText/369124 |
| _version_ | 1811317472807092224 |
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| author | Julien Tilleul Giuseppe Querques Vittorio Capuano Alexandra Miere Mayer Srour Eric H. Souied |
| author_facet | Julien Tilleul Giuseppe Querques Vittorio Capuano Alexandra Miere Mayer Srour Eric H. Souied |
| author_sort | Julien Tilleul |
| collection | DOAJ |
| description | Purpose: To report the case of a patient with unilateral idiopathic macular telangiectasia (IMT) associated with type 3 neovascularization. Methods: Observational case report. Results: We describe a case of an 85-year-old woman who presented at our department with a gradual vision loss in her left eye (LE). Her best-corrected visual acuity (BCVA) was 20/200 in the LE. Fundus examination showed 2 small hemorrhages located nasally to the LE fovea, as well as lipid exudates. Fluorescein angiography revealed early hyperfluorescence corresponding to the dilated capillaries. Spectral-domain optical coherence tomography (SD-OCT) showed several microaneurysms within the inner retinal layers. Late indocyanine green angiography revealed a focal hyperfluorescence corresponding to a type 3 neovascularization. No signs of IMT or type 3 neovascularization were detected in the right eye. Based on these findings, the patient was diagnosed with type 1 IMT and coincident type 3 neovascularization. The LE was treated with intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections. Twenty-four months later, SD-OCT revealed regression of the exudative signs, and LE BCVA improved to 20/100. Conclusion: We describe the case of an unusual association between older-onset IMT and type 3 neovascularization, and subsequent regression by anti-VEGF injections. We propose a new IMT subtype called type 1C for this association. Further research must be done in order to establish the pathophysiologic mechanism and likelihood of this association. |
| first_indexed | 2024-04-13T12:08:37Z |
| format | Article |
| id | doaj.art-c16a8478c75645f18e7e3d2d4b1c7a73 |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-04-13T12:08:37Z |
| publishDate | 2014-11-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-c16a8478c75645f18e7e3d2d4b1c7a732022-12-22T02:47:34ZengKarger PublishersCase Reports in Ophthalmology1663-26992014-11-015335235610.1159/000369124369124Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 NeovascularizationJulien TilleulGiuseppe QuerquesVittorio CapuanoAlexandra MiereMayer SrourEric H. SouiedPurpose: To report the case of a patient with unilateral idiopathic macular telangiectasia (IMT) associated with type 3 neovascularization. Methods: Observational case report. Results: We describe a case of an 85-year-old woman who presented at our department with a gradual vision loss in her left eye (LE). Her best-corrected visual acuity (BCVA) was 20/200 in the LE. Fundus examination showed 2 small hemorrhages located nasally to the LE fovea, as well as lipid exudates. Fluorescein angiography revealed early hyperfluorescence corresponding to the dilated capillaries. Spectral-domain optical coherence tomography (SD-OCT) showed several microaneurysms within the inner retinal layers. Late indocyanine green angiography revealed a focal hyperfluorescence corresponding to a type 3 neovascularization. No signs of IMT or type 3 neovascularization were detected in the right eye. Based on these findings, the patient was diagnosed with type 1 IMT and coincident type 3 neovascularization. The LE was treated with intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections. Twenty-four months later, SD-OCT revealed regression of the exudative signs, and LE BCVA improved to 20/100. Conclusion: We describe the case of an unusual association between older-onset IMT and type 3 neovascularization, and subsequent regression by anti-VEGF injections. We propose a new IMT subtype called type 1C for this association. Further research must be done in order to establish the pathophysiologic mechanism and likelihood of this association.http://www.karger.com/Article/FullText/369124Anti-vascular endothelial growth factorFluorescein angiographyIdiopathic macular telangiectasiaSpectral-domain optical coherence tomographyType 3 neovascularization |
| spellingShingle | Julien Tilleul Giuseppe Querques Vittorio Capuano Alexandra Miere Mayer Srour Eric H. Souied Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization Case Reports in Ophthalmology Anti-vascular endothelial growth factor Fluorescein angiography Idiopathic macular telangiectasia Spectral-domain optical coherence tomography Type 3 neovascularization |
| title | Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization |
| title_full | Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization |
| title_fullStr | Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization |
| title_full_unstemmed | Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization |
| title_short | Type 1 Idiopathic Macular Telangiectasia Associated with Type 3 Neovascularization |
| title_sort | type 1 idiopathic macular telangiectasia associated with type 3 neovascularization |
| topic | Anti-vascular endothelial growth factor Fluorescein angiography Idiopathic macular telangiectasia Spectral-domain optical coherence tomography Type 3 neovascularization |
| url | http://www.karger.com/Article/FullText/369124 |
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