Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review
Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reactio...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sultan Qaboos University
2013-08-01
|
| Series: | Sultan Qaboos University Medical Journal |
| Subjects: | |
| Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/1852 |
| _version_ | 1818494905938345984 |
|---|---|
| author | Aravind Narayanan Rohit R. Date Sanathkumar Birur Pradipta Bhakta Sinnakirouchenane Srinivasan |
| author_facet | Aravind Narayanan Rohit R. Date Sanathkumar Birur Pradipta Bhakta Sinnakirouchenane Srinivasan |
| author_sort | Aravind Narayanan |
| collection | DOAJ |
| description | Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature. |
| first_indexed | 2024-12-10T18:13:09Z |
| format | Article |
| id | doaj.art-c16f54fde4584f0cbd66ebbff1cdef01 |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-10T18:13:09Z |
| publishDate | 2013-08-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-c16f54fde4584f0cbd66ebbff1cdef012022-12-22T01:38:23ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282013-08-011334674711776Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature reviewAravind Narayanan0Rohit R. Date1Sanathkumar Birur2Pradipta Bhakta3Sinnakirouchenane Srinivasan4Department of Anaesthesia & Intensive Care, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Anaesthesia & Intensive Care, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Anaesthesia & Intensive Care, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Anaesthesia & Intensive Care, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Anaesthesia & Intensive Care, Sultan Qaboos University Hospital, Muscat, OmanHereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature.https://journals.squ.edu.om/index.php/squmj/article/view/1852anesthesiahereditary angioedemac1 esterase inhibitor deficiencycase reportoman. |
| spellingShingle | Aravind Narayanan Rohit R. Date Sanathkumar Birur Pradipta Bhakta Sinnakirouchenane Srinivasan Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review Sultan Qaboos University Medical Journal anesthesia hereditary angioedema c1 esterase inhibitor deficiency case report oman. |
| title | Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review |
| title_full | Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review |
| title_fullStr | Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review |
| title_full_unstemmed | Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review |
| title_short | Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor : Case report and literature review |
| title_sort | anaesthesia management of a patient with hereditary angioedema with prophylactic administration of c1 esterase inhibitor case report and literature review |
| topic | anesthesia hereditary angioedema c1 esterase inhibitor deficiency case report oman. |
| url | https://journals.squ.edu.om/index.php/squmj/article/view/1852 |
| work_keys_str_mv | AT aravindnarayanan anaesthesiamanagementofapatientwithhereditaryangioedemawithprophylacticadministrationofc1esteraseinhibitorcasereportandliteraturereview AT rohitrdate anaesthesiamanagementofapatientwithhereditaryangioedemawithprophylacticadministrationofc1esteraseinhibitorcasereportandliteraturereview AT sanathkumarbirur anaesthesiamanagementofapatientwithhereditaryangioedemawithprophylacticadministrationofc1esteraseinhibitorcasereportandliteraturereview AT pradiptabhakta anaesthesiamanagementofapatientwithhereditaryangioedemawithprophylacticadministrationofc1esteraseinhibitorcasereportandliteraturereview AT sinnakirouchenanesrinivasan anaesthesiamanagementofapatientwithhereditaryangioedemawithprophylacticadministrationofc1esteraseinhibitorcasereportandliteraturereview |