An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals

Objective: Blood pressure (BP) data can influence therapeutic decisions for some patients, while non-invasive devices that continuously monitor BP can provide patients with a more comprehensive BP assessment. Therefore, this study proposes a multi-sensor-based small cuffless BP monitoring device tha...

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Main Authors: Cheng-Yan Guo, Hao-Ching Chang, Kuan-Jen Wang, Tung-Li Hsieh
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/13/8/1327
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author Cheng-Yan Guo
Hao-Ching Chang
Kuan-Jen Wang
Tung-Li Hsieh
author_facet Cheng-Yan Guo
Hao-Ching Chang
Kuan-Jen Wang
Tung-Li Hsieh
author_sort Cheng-Yan Guo
collection DOAJ
description Objective: Blood pressure (BP) data can influence therapeutic decisions for some patients, while non-invasive devices that continuously monitor BP can provide patients with a more comprehensive BP assessment. Therefore, this study proposes a multi-sensor-based small cuffless BP monitoring device that integrates a piezoelectric sensor array and an optical sensor, which can monitor the patient’s physiological signals from the radial artery. Method: Based on the Moens–Korteweg (MK) equation of the hemodynamic model, pulse wave velocity (PWV) can be correlated with arterial compliance and BP can be estimated. Therefore, the novel method proposed in this study involves using a piezoelectric sensor array to measure the PWV and an optical sensor to measure the photoplethysmography (PPG) intensity ratio (PIR) signal to estimate the participant’s arterial parameters. The parameters measured by multiple sensors were combined to estimate BP based on the P–β model derived from the MK equation. Result: We recruited 20 participants for the BP monitoring experiment to compare the performance of the BP estimation method with the regression model and the P–β model method with arterial compliance. We then compared the estimated BP with a reference device for validation. The results are presented as the error mean ± standard deviation (SD). Based on the regression model method, systolic blood pressure (SBP) was 0.32 ± 5.94, diastolic blood pressure (DBP) was 2.17 ± 6.22, and mean arterial pressure (MAP) was 1.55 ± 5.83. The results of the P–β model method were as follows: SBP was 0.75 ± 3.9, DBP was 1.1 ± 3.12, and MAP was 0.49 ± 2.82. Conclusion: According to the results of our proposed small cuffless BP monitoring device, both methods of estimating BP conform to ANSI/AAMI/ISO 81060-2:20181_5.2.4.1.2 criterion 1 and 2, and using arterial parameters to calibrate the MK equation model can improve BP estimate accuracy. In the future, our proposed device can provide patients with a convenient and comfortable BP monitoring solution. Since the device is small, it can be used in a public place without attracting other people’s attention, thereby effectively improving the patient’s right to privacy, and increasing their willingness to use it.
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spelling doaj.art-c17856bcddd8442c87a428662236efe72023-12-02T00:01:53ZengMDPI AGMicromachines2072-666X2022-08-01138132710.3390/mi13081327An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical SignalsCheng-Yan Guo0Hao-Ching Chang1Kuan-Jen Wang2Tung-Li Hsieh3Accurate Meditech Inc., New Taipei City 241406, TaiwanAccurate Meditech Inc., New Taipei City 241406, TaiwanAccurate Meditech Inc., New Taipei City 241406, TaiwanDepartment of Electronic Engineering, National Kaohsiung University of Science and Technology, No. 415, Jiangong Rd., Sanmin Dist., Kaohsiung City 807618, TaiwanObjective: Blood pressure (BP) data can influence therapeutic decisions for some patients, while non-invasive devices that continuously monitor BP can provide patients with a more comprehensive BP assessment. Therefore, this study proposes a multi-sensor-based small cuffless BP monitoring device that integrates a piezoelectric sensor array and an optical sensor, which can monitor the patient’s physiological signals from the radial artery. Method: Based on the Moens–Korteweg (MK) equation of the hemodynamic model, pulse wave velocity (PWV) can be correlated with arterial compliance and BP can be estimated. Therefore, the novel method proposed in this study involves using a piezoelectric sensor array to measure the PWV and an optical sensor to measure the photoplethysmography (PPG) intensity ratio (PIR) signal to estimate the participant’s arterial parameters. The parameters measured by multiple sensors were combined to estimate BP based on the P–β model derived from the MK equation. Result: We recruited 20 participants for the BP monitoring experiment to compare the performance of the BP estimation method with the regression model and the P–β model method with arterial compliance. We then compared the estimated BP with a reference device for validation. The results are presented as the error mean ± standard deviation (SD). Based on the regression model method, systolic blood pressure (SBP) was 0.32 ± 5.94, diastolic blood pressure (DBP) was 2.17 ± 6.22, and mean arterial pressure (MAP) was 1.55 ± 5.83. The results of the P–β model method were as follows: SBP was 0.75 ± 3.9, DBP was 1.1 ± 3.12, and MAP was 0.49 ± 2.82. Conclusion: According to the results of our proposed small cuffless BP monitoring device, both methods of estimating BP conform to ANSI/AAMI/ISO 81060-2:20181_5.2.4.1.2 criterion 1 and 2, and using arterial parameters to calibrate the MK equation model can improve BP estimate accuracy. In the future, our proposed device can provide patients with a convenient and comfortable BP monitoring solution. Since the device is small, it can be used in a public place without attracting other people’s attention, thereby effectively improving the patient’s right to privacy, and increasing their willingness to use it.https://www.mdpi.com/2072-666X/13/8/1327Moens–Kortewegpulse wave velocityphotoplethysmographysystolic blood pressurediastolic blood pressure
spellingShingle Cheng-Yan Guo
Hao-Ching Chang
Kuan-Jen Wang
Tung-Li Hsieh
An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals
Micromachines
Moens–Korteweg
pulse wave velocity
photoplethysmography
systolic blood pressure
diastolic blood pressure
title An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals
title_full An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals
title_fullStr An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals
title_full_unstemmed An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals
title_short An Arterial Compliance Sensor for Cuffless Blood Pressure Estimation Based on Piezoelectric and Optical Signals
title_sort arterial compliance sensor for cuffless blood pressure estimation based on piezoelectric and optical signals
topic Moens–Korteweg
pulse wave velocity
photoplethysmography
systolic blood pressure
diastolic blood pressure
url https://www.mdpi.com/2072-666X/13/8/1327
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