From Normal to Obesity and Back: The Associations between Mitochondrial DNA Copy Number, Gender, and Body Mass Index

From Normal to Obesity and Back: The Associations between Mitochondrial DNA Copy Number, Gender, and Body Mass Index

Mitochondrial DNA (mtDNA) encodes core subunits of oxidative phosphorylation complexes and, as a result of intricate regulatory crosstalk between nuclear and mitochondrial genomes, the total number of mtDNA copies fits the requirements of each cell type. Deviations from the physiological number of m...

Full description

Bibliographic Details
Main Authors: Daria Skuratovskaia, Larisa Litvinova, Maria Vulf, Pavel Zatolokin, Konstantin Popadin, Ilia Mazunin
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
mtDNA copies
bariatric surgery
type 2 diabetes
obesity
ddPCR
Online Access:https://www.mdpi.com/2073-4409/8/5/430

Similar Items

Similar Items