Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase

Purpose. To study the efficacy of a developed method of non-surgical treatment of vitreomacular traction (VMT) using the bacterial collagenase.Material and methods. The study group included 65 cases of VMT with a length from 20 to 3100 μm. The VMT was isolated in 22 cases, and it was complicated in...

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Main Authors: P. V. Lyskin, V. D. Zakharov, A. A. Shpak, M. I. Zgoba, I. R. Makarenko
Format: Article
Language:Russian
Published: Publishing house "Ophthalmology" 2019-11-01
Series:Офтальмохирургия
Subjects:
Online Access:https://www.ophthalmosurgery.ru/jour/article/view/532
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author P. V. Lyskin
V. D. Zakharov
A. A. Shpak
M. I. Zgoba
I. R. Makarenko
author_facet P. V. Lyskin
V. D. Zakharov
A. A. Shpak
M. I. Zgoba
I. R. Makarenko
author_sort P. V. Lyskin
collection DOAJ
description Purpose. To study the efficacy of a developed method of non-surgical treatment of vitreomacular traction (VMT) using the bacterial collagenase.Material and methods. The study group included 65 cases of VMT with a length from 20 to 3100 μm. The VMT was isolated in 22 cases, and it was complicated in 43 cases: by macular hole (29 eyes) or epiretinal fibrosis (14 eyes).Results. In 3 cases (4.6%) within three months after the diagnosis there was a spontaneous resolution of traction with the restoration of the macular profile. In 48 cases (73.9%) an elimination of VMT after the treatment was achieved. In 14 cases (21.5%) VMT could not be eliminated. In 15 cases it was possible to achieve not only the elimination of VMT, but also the closure of macular hole. In 9 cases, it was possible to achieve the resolution of VMT and epiretinal fibrosis with the improved visual acuity.Conclusion. The obtained results showed that the developed method of non-surgical treatment of VMT can be the method of choice in the treatment of both isolated and complicated VMT of any length.
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spelling doaj.art-c17b9dff2e4f455ca4df2c8a5de292942023-01-20T12:34:51ZrusPublishing house "Ophthalmology"Офтальмохирургия0235-41602312-49702019-11-0103727710.25276/0235-4160-2019-3-72-77420Results of vitreomacular tractionnon-surgical treatment using bacterial collagenaseP. V. Lyskin0V. D. Zakharov1A. A. Shpak2M. I. Zgoba3I. R. Makarenko4The S. Fyodorov Eye Microsurgery Federal State InstitutionThe S. Fyodorov Eye Microsurgery Federal State InstitutionThe S. Fyodorov Eye Microsurgery Federal State InstitutionThe S. Fyodorov Eye Microsurgery Federal State InstitutionThe S. Fyodorov Eye Microsurgery Federal State InstitutionPurpose. To study the efficacy of a developed method of non-surgical treatment of vitreomacular traction (VMT) using the bacterial collagenase.Material and methods. The study group included 65 cases of VMT with a length from 20 to 3100 μm. The VMT was isolated in 22 cases, and it was complicated in 43 cases: by macular hole (29 eyes) or epiretinal fibrosis (14 eyes).Results. In 3 cases (4.6%) within three months after the diagnosis there was a spontaneous resolution of traction with the restoration of the macular profile. In 48 cases (73.9%) an elimination of VMT after the treatment was achieved. In 14 cases (21.5%) VMT could not be eliminated. In 15 cases it was possible to achieve not only the elimination of VMT, but also the closure of macular hole. In 9 cases, it was possible to achieve the resolution of VMT and epiretinal fibrosis with the improved visual acuity.Conclusion. The obtained results showed that the developed method of non-surgical treatment of VMT can be the method of choice in the treatment of both isolated and complicated VMT of any length.https://www.ophthalmosurgery.ru/jour/article/view/532vitreomacular tractionenzyme vitreolysisbacterial collagenase
spellingShingle P. V. Lyskin
V. D. Zakharov
A. A. Shpak
M. I. Zgoba
I. R. Makarenko
Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase
Офтальмохирургия
vitreomacular traction
enzyme vitreolysis
bacterial collagenase
title Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase
title_full Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase
title_fullStr Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase
title_full_unstemmed Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase
title_short Results of vitreomacular tractionnon-surgical treatment using bacterial collagenase
title_sort results of vitreomacular tractionnon surgical treatment using bacterial collagenase
topic vitreomacular traction
enzyme vitreolysis
bacterial collagenase
url https://www.ophthalmosurgery.ru/jour/article/view/532
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AT mizgoba resultsofvitreomaculartractionnonsurgicaltreatmentusingbacterialcollagenase
AT irmakarenko resultsofvitreomaculartractionnonsurgicaltreatmentusingbacterialcollagenase