Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults
IntroductionAlthough impacts of physical activity on cognitive functions have been intensively investigated, they are still far from being completely understood. The aim of this study was to evaluate the effect of 12 weeks of the Nordic Walking training with BungyPump resistance poles (NW-RSA) on th...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1151184/full |
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| author | Ewa Rodziewicz-Flis Ulana Juhas Jakub Antoni Kortas Joanna Jaworska Ilona Bidzan-Bluma Ilona Bidzan-Bluma Anna Babińska Katarzyna Micielska Małgorzata Żychowska Giovanni Lombardi Giovanni Lombardi Jędrzej Antosiewicz Ewa Ziemann |
| author_facet | Ewa Rodziewicz-Flis Ulana Juhas Jakub Antoni Kortas Joanna Jaworska Ilona Bidzan-Bluma Ilona Bidzan-Bluma Anna Babińska Katarzyna Micielska Małgorzata Żychowska Giovanni Lombardi Giovanni Lombardi Jędrzej Antosiewicz Ewa Ziemann |
| author_sort | Ewa Rodziewicz-Flis |
| collection | DOAJ |
| description | IntroductionAlthough impacts of physical activity on cognitive functions have been intensively investigated, they are still far from being completely understood. The aim of this study was to evaluate the effect of 12 weeks of the Nordic Walking training with BungyPump resistance poles (NW-RSA) on the amino acid and kynurenine profiles as well as selected myokine/exerkine concentrations, which may modify the interface between physical and cognitive functions.MethodsA group of 32 older adults participated in the study. Before and after the intervention, body composition, cognitive functions, and physical performance were assessed. Blood samples were taken before and 1 h after the first and last sessions of the NW-RSA training, to determine circulating levels of exercise-induced proteins, i.e., brain-derived neurotrophic factor (BDNF), irisin, kynurenine (KYN), metabolites, and amino acids.ResultsThe NW-RSA training induced a significant improvement in cognitive functions and physical performance as well as a reduction in fat mass (p = 0.05). Changes were accompanied by a decline in resting serum BDNF (p = 0.02) and a slight reduction in irisin concentration (p = 0.08). Still, changes in irisin concentration immediately after the NW-RSA intervention depended on shifts in kynurenine—irisin dropped as kynurenine increased. The kynurenine-to-tryptophan and phenylalanine-to-tyrosine ratios decreased significantly, suggesting their possible involvement in the amelioration of cognitive functions. No changes of glucose homeostasis or lipid profile were found. Shifts in the concentrations of selected amino acids might have covered the increased energy demand in response to the NW-RSA training and contributed to an improvement of physical performance.ConclusionRegular Nordic Walking training with additional resistance (BungyPump) improved cognitive functions and physical performance. These positive effects were associated with a reduced BDNF concentration and kynurenine-to-tryptophan ratio as well as changes in the amino acid profile. |
| first_indexed | 2024-03-12T01:34:31Z |
| format | Article |
| id | doaj.art-c17ef50700a14dd38db3a0038487db11 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-12T01:34:31Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-c17ef50700a14dd38db3a0038487db112023-09-11T12:20:37ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-09-011410.3389/fendo.2023.11511841151184Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adultsEwa Rodziewicz-Flis0Ulana Juhas1Jakub Antoni Kortas2Joanna Jaworska3Ilona Bidzan-Bluma4Ilona Bidzan-Bluma5Anna Babińska6Katarzyna Micielska7Małgorzata Żychowska8Giovanni Lombardi9Giovanni Lombardi10Jędrzej Antosiewicz11Ewa Ziemann12Department of Physiotherapy, Gdansk University of Physical Education and Sport, Gdansk, PolandDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Gdansk, PolandDepartment of Health and Natural Sciences, Gdansk University of Physical Education and Sport, Gdansk, PolandDepartment of Physiology, Medical University of Gdansk, Gdansk, PolandDepartment of Psychology, Gdansk University of Physical Education and Sport, Gdansk, PolandInstitute of Psychology, Faculty of Social Sciences, University of Gdansk, Gdansk, PolandDepartment of Endocrinology and Internal Medicine, Medical University of Gdansk, Gdansk, PolandDepartment of Physical Education and Lifelong Sports, Poznan University of Physical Education, Poznan, PolandDepartment of Biological Foundations of Physical Culture, Kazimierz Wielki University in Bydgoszcz, Bydgoszcz, Poland0Department of Athletics, Strength and Conditioning, Poznan University of Physical Education, Poznan, Poland1Laboratory of Experimental Biochemistry and Molecular Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Ortopedico Galeazzi, Milano, ItalyDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Gdansk, Poland0Department of Athletics, Strength and Conditioning, Poznan University of Physical Education, Poznan, PolandIntroductionAlthough impacts of physical activity on cognitive functions have been intensively investigated, they are still far from being completely understood. The aim of this study was to evaluate the effect of 12 weeks of the Nordic Walking training with BungyPump resistance poles (NW-RSA) on the amino acid and kynurenine profiles as well as selected myokine/exerkine concentrations, which may modify the interface between physical and cognitive functions.MethodsA group of 32 older adults participated in the study. Before and after the intervention, body composition, cognitive functions, and physical performance were assessed. Blood samples were taken before and 1 h after the first and last sessions of the NW-RSA training, to determine circulating levels of exercise-induced proteins, i.e., brain-derived neurotrophic factor (BDNF), irisin, kynurenine (KYN), metabolites, and amino acids.ResultsThe NW-RSA training induced a significant improvement in cognitive functions and physical performance as well as a reduction in fat mass (p = 0.05). Changes were accompanied by a decline in resting serum BDNF (p = 0.02) and a slight reduction in irisin concentration (p = 0.08). Still, changes in irisin concentration immediately after the NW-RSA intervention depended on shifts in kynurenine—irisin dropped as kynurenine increased. The kynurenine-to-tryptophan and phenylalanine-to-tyrosine ratios decreased significantly, suggesting their possible involvement in the amelioration of cognitive functions. No changes of glucose homeostasis or lipid profile were found. Shifts in the concentrations of selected amino acids might have covered the increased energy demand in response to the NW-RSA training and contributed to an improvement of physical performance.ConclusionRegular Nordic Walking training with additional resistance (BungyPump) improved cognitive functions and physical performance. These positive effects were associated with a reduced BDNF concentration and kynurenine-to-tryptophan ratio as well as changes in the amino acid profile.https://www.frontiersin.org/articles/10.3389/fendo.2023.1151184/fullexerkinesbrain-derived neurotrophic factoririsintraining physicalmental health |
| spellingShingle | Ewa Rodziewicz-Flis Ulana Juhas Jakub Antoni Kortas Joanna Jaworska Ilona Bidzan-Bluma Ilona Bidzan-Bluma Anna Babińska Katarzyna Micielska Małgorzata Żychowska Giovanni Lombardi Giovanni Lombardi Jędrzej Antosiewicz Ewa Ziemann Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults Frontiers in Endocrinology exerkines brain-derived neurotrophic factor irisin training physical mental health |
| title | Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults |
| title_full | Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults |
| title_fullStr | Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults |
| title_full_unstemmed | Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults |
| title_short | Nordic Walking training in BungyPump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults |
| title_sort | nordic walking training in bungypump form improves cognitive functions and physical performance and induces changes in amino acids and kynurenine profiles in older adults |
| topic | exerkines brain-derived neurotrophic factor irisin training physical mental health |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1151184/full |
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