A simplified purification protocol for recombinant adeno-associated virus vectors

A simplified purification protocol for recombinant adeno-associated virus vectors

We describe a new rapid, low cost, and scalable method for purification of various recombinant adeno-associated viruses (rAAVs) from the lysates of producer cells of either mammalian or insect origin. The method takes advantage of two general biochemical properties of all characterized AAV serotypes...

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Bibliographic Details
Main Authors:	Mark Potter, Bridget Lins, Mario Mietzsch, Regine Heilbronn, Kim Van Vliet, Paul Chipman, Mavis Agbandje-McKenna, Brian D Cleaver, Nathalie Clément, Barry J Byrne, Sergei Zolotukhin
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Series:	Molecular Therapy: Methods & Clinical Development
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050116301012

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