Succinate dehydrogenase as a new target for melatonin binding in the complex diabetes mellitus treatment

Succinate dehydrogenase as a new target for melatonin binding in the complex diabetes mellitus treatment

Relevance. Alloxan, destroying the beta cells of the pancreas, provokes hyperglycemia, which causes a hypoenergetic state. Mitochondrial succinate dehydrogenase dysfunction plays an important role in the pathogenesis of diabetes. Pharmacotherapy of diabetes mellitus has been and remains the subject...

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Bibliographic Details
Main Authors: Karine S. Elbekyan, Evgenia V. Markarova, Lernik S. Unanyan, Elena I. Diskaeva, Yurii V. Pervushin, Fatima A. Bidzhieva
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2022-12-01
Series:RUDN Journal of Medicine
Subjects:
diabetes
melatonin
succinate dehydrogenase (sdh)
molecular docking
Online Access:https://journals.rudn.ru/medicine/article/viewFile/32226/21246

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