PDGFRα-Signaling Is Dispensable for the Development of the Sinoatrial Node After Its Fate Commitment

Palate-derived growth factor receptor α (Pdgfrα) signaling has been reported to play important roles in the cardiac development. A previous study utilizing Pdgfrα conventional knockout mice reported hypoplasia of the sinus venous myocardium including the sinoatrial node (SAN) accompanied by increase...

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Hlavní autoři: Xi Zheng, Fengjiao Wang, Xiaoxiao Hu, Hua Li, Zhen Guan, Yanding Zhang, Xuefeng Hu
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2021-06-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2021.647165/full