In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys
Magnesium (Mg) alloys are adequate materials for orthopedic and maxilo-facial implants due to their biocompatibility, good mechanical properties closely related to the hard tissues, and processability. Their main drawbacks are the high-speed corrosion process and hydrogen release. In order to improv...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Biomimetics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2313-7673/8/7/526 |
| _version_ | 1827640453216862208 |
|---|---|
| author | Alexandru Streza Aurora Antoniac Veronica Manescu (Paltanea) Robert Ciocoiu Cosmin-Mihai Cotrut Marian Miculescu Florin Miculescu Iulian Antoniac Marco Fosca Julietta V. Rau Horatiu Dura |
| author_facet | Alexandru Streza Aurora Antoniac Veronica Manescu (Paltanea) Robert Ciocoiu Cosmin-Mihai Cotrut Marian Miculescu Florin Miculescu Iulian Antoniac Marco Fosca Julietta V. Rau Horatiu Dura |
| author_sort | Alexandru Streza |
| collection | DOAJ |
| description | Magnesium (Mg) alloys are adequate materials for orthopedic and maxilo-facial implants due to their biocompatibility, good mechanical properties closely related to the hard tissues, and processability. Their main drawbacks are the high-speed corrosion process and hydrogen release. In order to improve corrosion and mechanical properties, the Mg matrix can be strengthened through alloying elements with high temperature-dependent solubility materials. Rare earth elements (RE) contribute to mechanical properties and degradation improvement. Another possibility to reduce the corrosion rate of Mg-based alloys was demonstrated to be the different types of coatings (bioceramics, polymers, and composites) applied on their surface. The present investigation is related to the coating of two Mg-based alloys from the system Mg3Nd (Mg-Nd-Y-Zr-Zn) with polymeric-based composite coatings made from cellulose acetate (CA) combined with two fillers, respectively hydroxyapatite (HAp) and Mg particles. The main functions of the coatings are to reduce the biodegradation rate and to modify the surface properties in order to increase osteointegration. Firstly, the microstructural features of the experimental Mg3Nd alloys were revealed by optical microscopy and scanning electron microscopy (SEM) coupled with energy-dispersive spectroscopy. Apart from the surface morphology revealed by SEM, the roughness and wettability of all experimental samples were evaluated. The corrosion behavior of the uncoated and coated samples of both Mg3Nd alloys was investigated by immersion testing and electrochemical testing using Simulated Body Fluid as the medium. The complex in vitro research performed highlights that the composite coating based on CA with HAp particles exhibited the best protective effect for both Mg3Nd alloys. |
| first_indexed | 2024-03-09T16:59:43Z |
| format | Article |
| id | doaj.art-c185bf11bd3f4726bc34336cbc1af224 |
| institution | Directory Open Access Journal |
| issn | 2313-7673 |
| language | English |
| last_indexed | 2024-03-09T16:59:43Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj.art-c185bf11bd3f4726bc34336cbc1af2242023-11-24T14:31:36ZengMDPI AGBiomimetics2313-76732023-11-018752610.3390/biomimetics8070526In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd AlloysAlexandru Streza0Aurora Antoniac1Veronica Manescu (Paltanea)2Robert Ciocoiu3Cosmin-Mihai Cotrut4Marian Miculescu5Florin Miculescu6Iulian Antoniac7Marco Fosca8Julietta V. Rau9Horatiu Dura10Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, RomaniaIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, ItalyIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, ItalyFaculty of Medicine, Lucian Blaga University of Sibiu, 2A Lucian Blaga Street, 550169 Sibiu, RomaniaMagnesium (Mg) alloys are adequate materials for orthopedic and maxilo-facial implants due to their biocompatibility, good mechanical properties closely related to the hard tissues, and processability. Their main drawbacks are the high-speed corrosion process and hydrogen release. In order to improve corrosion and mechanical properties, the Mg matrix can be strengthened through alloying elements with high temperature-dependent solubility materials. Rare earth elements (RE) contribute to mechanical properties and degradation improvement. Another possibility to reduce the corrosion rate of Mg-based alloys was demonstrated to be the different types of coatings (bioceramics, polymers, and composites) applied on their surface. The present investigation is related to the coating of two Mg-based alloys from the system Mg3Nd (Mg-Nd-Y-Zr-Zn) with polymeric-based composite coatings made from cellulose acetate (CA) combined with two fillers, respectively hydroxyapatite (HAp) and Mg particles. The main functions of the coatings are to reduce the biodegradation rate and to modify the surface properties in order to increase osteointegration. Firstly, the microstructural features of the experimental Mg3Nd alloys were revealed by optical microscopy and scanning electron microscopy (SEM) coupled with energy-dispersive spectroscopy. Apart from the surface morphology revealed by SEM, the roughness and wettability of all experimental samples were evaluated. The corrosion behavior of the uncoated and coated samples of both Mg3Nd alloys was investigated by immersion testing and electrochemical testing using Simulated Body Fluid as the medium. The complex in vitro research performed highlights that the composite coating based on CA with HAp particles exhibited the best protective effect for both Mg3Nd alloys.https://www.mdpi.com/2313-7673/8/7/526magnesium alloysbiodegradable alloysMg3Nd alloyscellulose acetate composite coatingscorrosionsurface |
| spellingShingle | Alexandru Streza Aurora Antoniac Veronica Manescu (Paltanea) Robert Ciocoiu Cosmin-Mihai Cotrut Marian Miculescu Florin Miculescu Iulian Antoniac Marco Fosca Julietta V. Rau Horatiu Dura In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys Biomimetics magnesium alloys biodegradable alloys Mg3Nd alloys cellulose acetate composite coatings corrosion surface |
| title | In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys |
| title_full | In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys |
| title_fullStr | In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys |
| title_full_unstemmed | In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys |
| title_short | In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys |
| title_sort | in vitro studies regarding the effect of cellulose acetate based composite coatings on the functional properties of the biodegradable mg3nd alloys |
| topic | magnesium alloys biodegradable alloys Mg3Nd alloys cellulose acetate composite coatings corrosion surface |
| url | https://www.mdpi.com/2313-7673/8/7/526 |
| work_keys_str_mv | AT alexandrustreza invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT auroraantoniac invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT veronicamanescupaltanea invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT robertciocoiu invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT cosminmihaicotrut invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT marianmiculescu invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT florinmiculescu invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT iulianantoniac invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT marcofosca invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT juliettavrau invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys AT horatiudura invitrostudiesregardingtheeffectofcelluloseacetatebasedcompositecoatingsonthefunctionalpropertiesofthebiodegradablemg3ndalloys |