Strain-, Sex-, and Time-Dependent Antidepressant-like Effects of Cannabidiol

Strain-, Sex-, and Time-Dependent Antidepressant-like Effects of Cannabidiol

Cannabidiol (CBD) is a non-intoxicating compound extracted from <i>Cannabis sativa</i>, showing antidepressant-like effects in different rodent models. However, inconsistent results have been described depending on the species and the strain used to assess depressive-like behavior. Moreo...

Full description

Bibliographic Details
Main Authors:	Gabriela P. Silote, Michelle C. Gatto, Amanda Eskelund, Francisco S. Guimarães, Gregers Wegener, Sâmia R. L. Joca
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Pharmaceuticals
Subjects:	cannabidiol S-ketamine sex mice strain Flinders Sensitive Line rats Flinders Resistant Lines rats
Online Access:	https://www.mdpi.com/1424-8247/14/12/1269

Similar Items

Depression-Associated Gene <i>Negr1-Fgfr2</i> Pathway Is Altered by Antidepressant Treatment
by: Lucia Carboni, et al.
Published: (2020-07-01)

New and old hotspots for rickettsial spotted fever acquired in Tasmania, 2012–2017
by: Gabriela Willis, et al.
Published: (2019-08-01)

Rickettsia honei Infection in Human, Nepal, 2009
by: Holly Murphy, et al.
Published: (2011-10-01)

Dynamics and Seasonality of the Leeuwin Current and the Surrounding Counter-Current System in the Region South of Western Australia
by: Mohd Fadzil Akhir, et al.
Published: (2020-07-01)

Rickettsia Detected in the Reptile Tick Bothriocroton hydrosauri from the Lizard Tiliqua rugosa in South Australia
by: Harriet Whiley, et al.
Published: (2016-06-01)

A randomized controlled trial evaluating the effectiveness of a self-management program for adolescents with a chronic condition: a study protocol
by: Jaunna Gauci, et al.
Published: (2022-10-01)

Matthew Flinders et la mise en cartes d’un nouvel espace indo-pacifique
by: Dany Bréelle
Published: (2016-12-01)

Comparison of Biosafety and Diagnostic Utility of Biosample Collection Cards
by: Hanna Keck, et al.
Published: (2022-10-01)

Comparison of short and long forms of the Flinders program of chronic disease SELF-management for participants starting SGLT-2 inhibitors for congestive heart failure (SELFMAN-HF): protocol for a prospective, observational study
by: Pupalan Iyngkaran, et al.
Published: (2023-05-01)

Odvrácená tvář otce egyptské archeologie William Matthew Flinders Petrie a eugenická věda // The Dark Side of the Father of Egyptian Archaeology William Matthew Flinders Petrie and Eugenic Science
by: Kamila Tomášková
Published: (2016-06-01)

Sensitivity of RNA viral nucleic acid-based detection of avian influenza virus, Newcastle disease virus, and African horse sickness virus on flinders technology associates card using conventional reverse-transcription polymerase chain reaction
by: Khate Rattanamas, et al.
Published: (2022-11-01)

Combined Low Dose of Ketamine and Social Isolation: A Possible Model of Induced Chronic Schizophrenia-Like Symptoms in Male Albino Rats
by: Suzanne Estaphan, et al.
Published: (2021-07-01)

Changes in Lipid Profile of Keratinocytes from Rat Skin Exposed to Chronic UVA or UVB Radiation and Topical Application of Cannabidiol
by: Wojciech Łuczaj, et al.
Published: (2020-11-01)

Identification of Groundwater Potential Recharge Zones in Flinders Ranges, South Australia Using Remote Sensing, GIS, and MIF Techniques
by: Alaa Ahmed, et al.
Published: (2021-09-01)

Diclofenac and dexamethasone modulate the effect of cannabidiol on the rat colon motility ex vivo
by: Chłopecka Magdalena, et al.
Published: (2023-06-01)

Sex Differences in the Neuropsychiatric Effects and Pharmacokinetics of Cannabidiol: A Scoping Review
by: Justin Matheson, et al.
Published: (2022-10-01)

Analyses of anaesthesia with ketamine combined with different sedatives in rats
by: A.M. Molina, et al.
Published: (2015-07-01)

Aromatase inhibition and ketamine in rats: sex-differences in antidepressant-like efficacy
by: Sandra Ledesma-Corvi, et al.
Published: (2023-10-01)

Crocins, the Bioactive Components of <i>Crocus sativus</i> L., Counteract the Disrupting Effects of Anesthetic Ketamine on Memory in Rats
by: Nikolaos Pitsikas, et al.
Published: (2021-01-01)

Oxidative Stress and Its Consequences in the Blood of Rats Irradiated with UV: Protective Effect of Cannabidiol
by: Michał Biernacki, et al.
Published: (2021-05-01)

Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model
by: María Salud García-Gutiérrez, et al.
Published: (2023-04-01)

Sıçanlarda ve Farelerde Yaşam Alanı Kriterleri
by: Emre Eren, et al.
Published: (2024-03-01)

Specific deletion of Axin1 leads to activation of β-catenin/BMP signaling resulting in fibular hemimelia phenotype in mice
by: Rong Xie, et al.
Published: (2022-12-01)

Functional characterization of cannabidiol effect on the serotonergic neurons of the dorsal raphe nucleus in rat brain slices
by: Aitziber Mendiguren, et al.
Published: (2022-09-01)

Walk Locomotion Kinematic Changes in a Model of Penetrating Hippocampal Injury in Male/Female Mice and Rats
by: Jonatan Alpirez, et al.
Published: (2023-11-01)

Rodents Prefer Going Downhill All the Way (Gravitaxis) Instead of Taking an Uphill Task
by: Yehonatan Ben-Shaul, et al.
Published: (2022-07-01)

Starting with mice, rats, and gerbils /
by: Gassner, Georg., et al.
Published: (1997)

Design and Development of a Compact Rat-Race Coupler
by: S. Ahirwar, et al.
Published: (2019-06-01)

Dose-Dependent Antidepressant-Like Effects of Cannabidiol in Aged Rats
by: Elena Hernández-Hernández, et al.
Published: (2022-07-01)

Cannabidiol Decreases Intestinal Inflammation in the Ovariectomized Murine Model of Postmenopause
by: Karen Mae A. Bacalia, et al.
Published: (2022-12-01)

A systematic review of the development and application of home cage monitoring in laboratory mice and rats
by: Pia Kahnau, et al.
Published: (2023-11-01)

Patterns of Gastrointestinal Helminth Infections in Rattus rattus, Rattus norvegicus, and Mus musculus in Chile
by: Alexandra Grandón-Ojeda, et al.
Published: (2022-06-01)

The Nitric Oxide (NO) Donor Molsidomine Counteract Social Withdrawal and Cognition Deficits Induced by Blockade of the NMDA Receptor in the Rat
by: Lamprini Katsanou, et al.
Published: (2023-04-01)

Regulation of DNA Methylation by Cannabidiol and Its Implications for Psychiatry: New Insights from In Vivo and In Silico Models
by: Luana B. Domingos, et al.
Published: (2022-11-01)

Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses (Equus caballus)
by: Alexander C. S. Thomson, et al.
Published: (2024-04-01)

Safety and efficacy of cannabidiol-cannabidiolic acid rich hemp extract in the treatment of refractory epileptic seizures in dogs
by: Gabriel A. Garcia, et al.
Published: (2022-07-01)

Cannabidiol Modulates the Motivational and Anxiety-Like Effects of 3,4-Methylenedioxypyrovalerone (MDPV) in Mice
by: Laia Alegre-Zurano, et al.
Published: (2021-08-01)

REDERIVATION BY EMBRYO TRANSFER IN STRAINS OF LABORATORY MICE AND RATS
by: S. Ya. Amstislavsky, et al.
Published: (2014-12-01)

Evaluation of the efficacy of a cannabidiol and cannabidiolic acid rich hemp extract for pain in dogs following a tibial plateau leveling osteotomy
by: Sarah Klatzkow, et al.
Published: (2023-01-01)

Pharmacokinetics of cannabidiol-/cannabidiolic acid-rich hemp oil in juvenile cynomolgus macaques (Macaca fascicularis)
by: Tinika N. Johns, et al.
Published: (2023-11-01)