The effect of gestational hypertension on the maternal mean platelet volume

To evaluate the effect of gestational hypertension on the maternal mean platelet volume (MPV). The study group comprised pregnant women with gestational hypertension who gave birth to single, term, healthy fetuses and control group was pregnant women without any complications. MPVs were calculated w...

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Main Authors: Emre Baser, Funda Salgur, Melek Bilge, Safak Ozdemirci, Deniz Esinler, Eylem Unlubilgin, Aykan Yucel, Ozlem Moraloglu Tekin
Format: Article
Language:English
Published: Society of Turaz Bilim 2020-03-01
Series:Medicine Science
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=64218
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author Emre Baser
Funda Salgur
Melek Bilge
Safak Ozdemirci
Deniz Esinler
Eylem Unlubilgin
Aykan Yucel
Ozlem Moraloglu Tekin
author_facet Emre Baser
Funda Salgur
Melek Bilge
Safak Ozdemirci
Deniz Esinler
Eylem Unlubilgin
Aykan Yucel
Ozlem Moraloglu Tekin
author_sort Emre Baser
collection DOAJ
description To evaluate the effect of gestational hypertension on the maternal mean platelet volume (MPV). The study group comprised pregnant women with gestational hypertension who gave birth to single, term, healthy fetuses and control group was pregnant women without any complications. MPVs were calculated within 24 hours in the intrapartum period. The mean MPV of 68 hypertensive and randomly selected 135 normotensive pregnant women were compared. The MPV of gestational hypertensive group was significantly higher (9.5±0.98 vs 9.2±0.9 fL; p=0.015). Using ROC analysis, the optimal MPV cut off value was found 9.25 fL with the sensitivity of 60.0% and the specificity of 61.0% (AUC=0.622, 95% CI=0.538-0.707, p=0.004) for the prediction of gestational hypertension. This study demonstrated that maternal MPV cannot be used to predict gestational hypertension in clinical practice due to its low sensitivity and specificity. However, further studies are needed to examine the predictive value of MPV in the progression of the hypertensive diseases of pregnancy. [Med-Science 2020; 9(1.000): 90-3]
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spelling doaj.art-c18bcb025651487784d8beef665d9c672024-02-03T08:38:23ZengSociety of Turaz BilimMedicine Science2147-06342020-03-019190310.5455/medscience.2018.08.914364218The effect of gestational hypertension on the maternal mean platelet volumeEmre Baser0Funda SalgurMelek BilgeSafak OzdemirciDeniz EsinlerEylem UnlubilginAykan YucelOzlem Moraloglu TekinYozgat Bozok University, Faculty of Medicine, Department of Obstetric and Gynecology, Yozgat,Turkey Baskent University, Faculty of Medicine, Department of Family Medicine, Ankara, Turkey Dr. Ali Kemal Belviranli Women Birth And Child Diseases Hospital, Department of Obstetric and Gynecology, Konya, Turkey Etlik Zubeyde Hanim Womens Health Education and Research Hospital, Department of Obstetrics and Gynecology, Ankara, Turkey Etlik Zubeyde Hanim Womens Health Education and Research Hospital, Department of Obstetrics and Gynecology, Perinatology High Risk Pregnancy Clinic, Ankara, TurkeyTo evaluate the effect of gestational hypertension on the maternal mean platelet volume (MPV). The study group comprised pregnant women with gestational hypertension who gave birth to single, term, healthy fetuses and control group was pregnant women without any complications. MPVs were calculated within 24 hours in the intrapartum period. The mean MPV of 68 hypertensive and randomly selected 135 normotensive pregnant women were compared. The MPV of gestational hypertensive group was significantly higher (9.5±0.98 vs 9.2±0.9 fL; p=0.015). Using ROC analysis, the optimal MPV cut off value was found 9.25 fL with the sensitivity of 60.0% and the specificity of 61.0% (AUC=0.622, 95% CI=0.538-0.707, p=0.004) for the prediction of gestational hypertension. This study demonstrated that maternal MPV cannot be used to predict gestational hypertension in clinical practice due to its low sensitivity and specificity. However, further studies are needed to examine the predictive value of MPV in the progression of the hypertensive diseases of pregnancy. [Med-Science 2020; 9(1.000): 90-3]http://www.ejmanager.com/fulltextpdf.php?mno=64218pregnancygestational hypertensionmean platelet volume
spellingShingle Emre Baser
Funda Salgur
Melek Bilge
Safak Ozdemirci
Deniz Esinler
Eylem Unlubilgin
Aykan Yucel
Ozlem Moraloglu Tekin
The effect of gestational hypertension on the maternal mean platelet volume
Medicine Science
pregnancy
gestational hypertension
mean platelet volume
title The effect of gestational hypertension on the maternal mean platelet volume
title_full The effect of gestational hypertension on the maternal mean platelet volume
title_fullStr The effect of gestational hypertension on the maternal mean platelet volume
title_full_unstemmed The effect of gestational hypertension on the maternal mean platelet volume
title_short The effect of gestational hypertension on the maternal mean platelet volume
title_sort effect of gestational hypertension on the maternal mean platelet volume
topic pregnancy
gestational hypertension
mean platelet volume
url http://www.ejmanager.com/fulltextpdf.php?mno=64218
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