High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta
Coverage of tuberculosis preventive treatment (TPT) in Indonesia is inadequate, and persons who start TPT often do not complete treatment. In 2020, Zero TB Yogyakarta implemented person-centered contact investigation and shorter TPT regimen provision in collaboration with primary health care centers...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/8/12/520 |
| _version_ | 1827573447269548032 |
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| author | Felisia Felisia Rina Triasih Betty Weri Yolanda Nababan Guardian Yoki Sanjaya Setyogati Candra Dewi Endang Sri Rahayu Lana Unwanah Philipp du Cros Geoffrey Chan |
| author_facet | Felisia Felisia Rina Triasih Betty Weri Yolanda Nababan Guardian Yoki Sanjaya Setyogati Candra Dewi Endang Sri Rahayu Lana Unwanah Philipp du Cros Geoffrey Chan |
| author_sort | Felisia Felisia |
| collection | DOAJ |
| description | Coverage of tuberculosis preventive treatment (TPT) in Indonesia is inadequate, and persons who start TPT often do not complete treatment. In 2020, Zero TB Yogyakarta implemented person-centered contact investigation and shorter TPT regimen provision in collaboration with primary health care centers. Between 1 January 2020 and 31 August 2022, we assessed eligibility for TPT among household contacts of persons with bacteriologically confirmed TB (index cases) and offered them a 3-month TPT regimen (3RH or 3HP). A dedicated nurse monitored contacts on TPT for treatment adherence and side effects every week in the first month and every two weeks in the next months. Contacts were also able to contact a nurse by phone or ask for home visits at any point if they had any concerns. A total of 1016 contacts were eligible for TPT: 772 (78.8%) started short regimen TPT with 706 (91.5%) completing their TPT. Side effects were reported in 26 (39%) of the non-completion group. We conclude that high rates of TPT uptake and completion among contacts assessed as eligible for TPT can be achieved through person-centered care and the use of shorter regimens. Side-effect monitoring and management while on TPT is vital for improving TPT completion. |
| first_indexed | 2024-03-08T20:19:26Z |
| format | Article |
| id | doaj.art-c18ce305572d485cb1ef885625da71b5 |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-08T20:19:26Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-c18ce305572d485cb1ef885625da71b52023-12-22T14:46:28ZengMDPI AGTropical Medicine and Infectious Disease2414-63662023-12-0181252010.3390/tropicalmed8120520High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in YogyakartaFelisia Felisia0Rina Triasih1Betty Weri Yolanda Nababan2Guardian Yoki Sanjaya3Setyogati Candra Dewi4Endang Sri Rahayu5Lana Unwanah6Philipp du Cros7Geoffrey Chan8Centre for Tropical Medicine, Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University, Sleman 55281, Yogyakarta, IndonesiaCentre for Tropical Medicine, Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University, Sleman 55281, Yogyakarta, IndonesiaCentre for Tropical Medicine, Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University, Sleman 55281, Yogyakarta, IndonesiaDepartment of Health Policy and Management, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Sleman 55281, Yogyakarta, IndonesiaYogyakarta City Health Office, Yogyakarta 55165, Yogyakarta, IndonesiaYogyakarta City Health Office, Yogyakarta 55165, Yogyakarta, IndonesiaYogyakarta City Health Office, Yogyakarta 55165, Yogyakarta, IndonesiaTuberculosis Elimination and Implementation Science Working Group, Burnet Institute, Melbourne, VIC 3004, AustraliaTuberculosis Elimination and Implementation Science Working Group, Burnet Institute, Melbourne, VIC 3004, AustraliaCoverage of tuberculosis preventive treatment (TPT) in Indonesia is inadequate, and persons who start TPT often do not complete treatment. In 2020, Zero TB Yogyakarta implemented person-centered contact investigation and shorter TPT regimen provision in collaboration with primary health care centers. Between 1 January 2020 and 31 August 2022, we assessed eligibility for TPT among household contacts of persons with bacteriologically confirmed TB (index cases) and offered them a 3-month TPT regimen (3RH or 3HP). A dedicated nurse monitored contacts on TPT for treatment adherence and side effects every week in the first month and every two weeks in the next months. Contacts were also able to contact a nurse by phone or ask for home visits at any point if they had any concerns. A total of 1016 contacts were eligible for TPT: 772 (78.8%) started short regimen TPT with 706 (91.5%) completing their TPT. Side effects were reported in 26 (39%) of the non-completion group. We conclude that high rates of TPT uptake and completion among contacts assessed as eligible for TPT can be achieved through person-centered care and the use of shorter regimens. Side-effect monitoring and management while on TPT is vital for improving TPT completion.https://www.mdpi.com/2414-6366/8/12/520tuberculosis preventive treatment (TPT)short regimenperson-centered care |
| spellingShingle | Felisia Felisia Rina Triasih Betty Weri Yolanda Nababan Guardian Yoki Sanjaya Setyogati Candra Dewi Endang Sri Rahayu Lana Unwanah Philipp du Cros Geoffrey Chan High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta Tropical Medicine and Infectious Disease tuberculosis preventive treatment (TPT) short regimen person-centered care |
| title | High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta |
| title_full | High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta |
| title_fullStr | High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta |
| title_full_unstemmed | High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta |
| title_short | High Tuberculosis Preventive Treatment Uptake and Completion Rates Using a Person-Centered Approach among Tuberculosis Household Contact in Yogyakarta |
| title_sort | high tuberculosis preventive treatment uptake and completion rates using a person centered approach among tuberculosis household contact in yogyakarta |
| topic | tuberculosis preventive treatment (TPT) short regimen person-centered care |
| url | https://www.mdpi.com/2414-6366/8/12/520 |
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