Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model
<p>Abstract</p> <p>Background</p> <p>To determine whether oral administration of geranylgeranylacetone (GGA), a nontoxic anti-ulcer drug that is an inducer of heat shock protein (HSP) 70, protects against drug-induced lung injury/fibrosis <it>in vivo</it>.&l...
Main Authors: | Hasegawa Yoshinori, Jijiwa Mayumi, Hashimoto Naozumi, Fujibayashi Takayoshi, Kojima Toshihisa, Ishiguro Naoki |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-09-01
|
Series: | BMC Pulmonary Medicine |
Online Access: | http://www.biomedcentral.com/1471-2466/9/45 |
Similar Items
-
Induction of heat-shock protein 70 expression by geranylgeranylacetone shows cytoprotective effects in cardiomyocytes of mice under humid heat stress.
by: Xiaowu Wang, et al.
Published: (2014-01-01) -
Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System
by: Tiancheng Jin, et al.
Published: (2023-08-01) -
Geranylgeranylacetone Ameliorates Beta-Amyloid Toxicity and Extends Lifespan via the Heat Shock Response in Caenorhabditis elegans
by: Isiah Mossiah, et al.
Published: (2022-04-01) -
Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy.
by: Atsushi Sanbe, et al.
Published: (2009-01-01) -
Geranylgeranylacetone reduces cardiomyocyte stiffness and attenuates diastolic dysfunction in a rat model of cardiometabolic syndrome
by: Mark T. Waddingham, et al.
Published: (2023-11-01)