Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates.

Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates.

The contractile response of the heart can be altered by disease-related protein modifications to numerous contractile proteins. By utilizing an IAANS labeled fluorescent troponin C, [Formula: see text], we examined the effects of ten disease-related troponin modifications on the Ca(2+) binding prope...

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Bibliographic Details
Main Authors:	Bin Liu, Svetlana B Tikunova, Kristopher P Kline, Jalal K Siddiqui, Jonathan P Davis
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3366952?pdf=render

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