Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech
The motivation of someone who is locked-in, that is, paralyzed and mute, is to find relief for their loss of function. The data presented in this report is part of an attempt to restore one of those lost functions, namely, speech. An essential feature of the development of a speech prosthesis is opt...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2022.874199/full |
| _version_ | 1818010077816160256 |
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| author | Ananya Ganesh Andre J. Cervantes Philip R. Kennedy |
| author_facet | Ananya Ganesh Andre J. Cervantes Philip R. Kennedy |
| author_sort | Ananya Ganesh |
| collection | DOAJ |
| description | The motivation of someone who is locked-in, that is, paralyzed and mute, is to find relief for their loss of function. The data presented in this report is part of an attempt to restore one of those lost functions, namely, speech. An essential feature of the development of a speech prosthesis is optimal decoding of patterns of recorded neural signals during silent or covert speech, that is, speaking “inside the head” with output that is inaudible due to the paralysis of the articulators. The aim of this paper is to illustrate the importance of both fast and slow single unit firings recorded from an individual with locked-in syndrome and from an intact participant speaking silently. Long duration electrodes were implanted in the motor speech cortex for up to 13 years in the locked-in participant. The data herein provide evidence that slow firing single units are essential for optimal decoding accuracy. Additional evidence indicates that slow firing single units can be conditioned in the locked-in participant 5 years after implantation, further supporting their role in decoding. |
| first_indexed | 2024-04-14T05:50:49Z |
| format | Article |
| id | doaj.art-c191cd5c2c724e5b85edcd56968a15ac |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-04-14T05:50:49Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-c191cd5c2c724e5b85edcd56968a15ac2022-12-22T02:09:07ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612022-08-011610.3389/fnhum.2022.874199874199Slow Firing Single Units Are Essential for Optimal Decoding of Silent SpeechAnanya Ganesh0Andre J. Cervantes1Philip R. Kennedy2Neural Signals Inc., Neural Prostheses Laboratory, Duluth, GA, United StatesBelize International Institute of Neuroscience, Belize City, BelizeNeural Signals Inc., Neural Prostheses Laboratory, Duluth, GA, United StatesThe motivation of someone who is locked-in, that is, paralyzed and mute, is to find relief for their loss of function. The data presented in this report is part of an attempt to restore one of those lost functions, namely, speech. An essential feature of the development of a speech prosthesis is optimal decoding of patterns of recorded neural signals during silent or covert speech, that is, speaking “inside the head” with output that is inaudible due to the paralysis of the articulators. The aim of this paper is to illustrate the importance of both fast and slow single unit firings recorded from an individual with locked-in syndrome and from an intact participant speaking silently. Long duration electrodes were implanted in the motor speech cortex for up to 13 years in the locked-in participant. The data herein provide evidence that slow firing single units are essential for optimal decoding accuracy. Additional evidence indicates that slow firing single units can be conditioned in the locked-in participant 5 years after implantation, further supporting their role in decoding.https://www.frontiersin.org/articles/10.3389/fnhum.2022.874199/fullneural signalsNeurotrophic electrodesingle unit firingsspeech prosthesislocked-in participants |
| spellingShingle | Ananya Ganesh Andre J. Cervantes Philip R. Kennedy Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech Frontiers in Human Neuroscience neural signals Neurotrophic electrode single unit firings speech prosthesis locked-in participants |
| title | Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech |
| title_full | Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech |
| title_fullStr | Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech |
| title_full_unstemmed | Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech |
| title_short | Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech |
| title_sort | slow firing single units are essential for optimal decoding of silent speech |
| topic | neural signals Neurotrophic electrode single unit firings speech prosthesis locked-in participants |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2022.874199/full |
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