Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies.
Epidemiological studies have investigated the potential anticancer effects of mushroom intake. This review aims to clarify the evidence on the association of dietary mushroom intake with breast cancer risk and to quantify its dose-response relationship. Relevant studies were identified by a search o...
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| Format: | Article |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3972098?pdf=render |
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| author | Jiaoyuan Li Li Zou Wei Chen Beibei Zhu Na Shen Juntao Ke Jiao Lou Ranran Song Rong Zhong Xiaoping Miao |
| author_facet | Jiaoyuan Li Li Zou Wei Chen Beibei Zhu Na Shen Juntao Ke Jiao Lou Ranran Song Rong Zhong Xiaoping Miao |
| author_sort | Jiaoyuan Li |
| collection | DOAJ |
| description | Epidemiological studies have investigated the potential anticancer effects of mushroom intake. This review aims to clarify the evidence on the association of dietary mushroom intake with breast cancer risk and to quantify its dose-response relationship. Relevant studies were identified by a search of PubMed, Web of Science and Google Scholar up to December 31, 2013. Observational studies with relative risks (RRs) or hazard ratios (HRs) or odd ratios (ORs) and 95% confidence intervals (CIs) of breast cancer for three or more categories of mushroom intake were eligible. The quality of included studies was assessed by using Newcastle-Ottawa Scale. A dose-response meta-analysis was performed by utilizing generalized least squares trend estimation. Eight case-control studies and two cohort studies with a total of 6890 cases were ultimately included. For dose-response analysis, there was no evidence of non-linear association between mushroom consumption and breast cancer risk (P = 0.337) and a 1 g/d increment in mushroom intake conferred an RR of 0.97 (95% CI: 0.96-0.98) for breast cancer risk, with moderate heterogeneity (I(2) = 56.3%, P = 0.015). Besides, available menopause data extracted from included studies were used to evaluate the influence of menopausal statues. The summary RRs of mushroom consumption on breast cancer were 0.96 (95% CI: 0.91-1.00) for premenopausal women and 0.94 (95% CI: 0.91-0.97) for postmenopausal women, respectively. Our findings demonstrated that mushroom intake may be inversely associated with risk of breast cancer, which need to be confirmed with large-scale prospective studies further. |
| first_indexed | 2024-12-11T06:12:51Z |
| format | Article |
| id | doaj.art-c1940b9d0fac4988bc4ee4a4e20b8153 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T06:12:51Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c1940b9d0fac4988bc4ee4a4e20b81532022-12-22T01:18:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9343710.1371/journal.pone.0093437Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies.Jiaoyuan LiLi ZouWei ChenBeibei ZhuNa ShenJuntao KeJiao LouRanran SongRong ZhongXiaoping MiaoEpidemiological studies have investigated the potential anticancer effects of mushroom intake. This review aims to clarify the evidence on the association of dietary mushroom intake with breast cancer risk and to quantify its dose-response relationship. Relevant studies were identified by a search of PubMed, Web of Science and Google Scholar up to December 31, 2013. Observational studies with relative risks (RRs) or hazard ratios (HRs) or odd ratios (ORs) and 95% confidence intervals (CIs) of breast cancer for three or more categories of mushroom intake were eligible. The quality of included studies was assessed by using Newcastle-Ottawa Scale. A dose-response meta-analysis was performed by utilizing generalized least squares trend estimation. Eight case-control studies and two cohort studies with a total of 6890 cases were ultimately included. For dose-response analysis, there was no evidence of non-linear association between mushroom consumption and breast cancer risk (P = 0.337) and a 1 g/d increment in mushroom intake conferred an RR of 0.97 (95% CI: 0.96-0.98) for breast cancer risk, with moderate heterogeneity (I(2) = 56.3%, P = 0.015). Besides, available menopause data extracted from included studies were used to evaluate the influence of menopausal statues. The summary RRs of mushroom consumption on breast cancer were 0.96 (95% CI: 0.91-1.00) for premenopausal women and 0.94 (95% CI: 0.91-0.97) for postmenopausal women, respectively. Our findings demonstrated that mushroom intake may be inversely associated with risk of breast cancer, which need to be confirmed with large-scale prospective studies further.http://europepmc.org/articles/PMC3972098?pdf=render |
| spellingShingle | Jiaoyuan Li Li Zou Wei Chen Beibei Zhu Na Shen Juntao Ke Jiao Lou Ranran Song Rong Zhong Xiaoping Miao Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. PLoS ONE |
| title | Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. |
| title_full | Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. |
| title_fullStr | Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. |
| title_full_unstemmed | Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. |
| title_short | Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. |
| title_sort | dietary mushroom intake may reduce the risk of breast cancer evidence from a meta analysis of observational studies |
| url | http://europepmc.org/articles/PMC3972098?pdf=render |
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