Desmoid abdominal tumour: A clinical case report and brief literature review
Desmoid tumors are unique mesenchymal neoplasm. They are able to spread to proximal tissues but tend not to metastasize. Our case presents a 66-year-old female referred for evaluation of the prominent, palpable mass located into the left abdomen. Imaging studies revealed a tumor up to 22 cm, extendi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-07-01
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| Series: | Gastroenterology Insights |
| Subjects: | |
| Online Access: | https://www.pagepress.org/journals/index.php/gi/article/view/6665 |
| _version_ | 1818028270020460544 |
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| author | Irina Ivanova Shahswar Arif Dinko Dinev Kalin Kalchev Maria Atanassova Iskren Kotzev |
| author_facet | Irina Ivanova Shahswar Arif Dinko Dinev Kalin Kalchev Maria Atanassova Iskren Kotzev |
| author_sort | Irina Ivanova |
| collection | DOAJ |
| description | Desmoid tumors are unique mesenchymal neoplasm. They are able to spread to proximal tissues but tend not to metastasize. Our case presents a 66-year-old female referred for evaluation of the prominent, palpable mass located into the left abdomen. Imaging studies revealed a tumor up to 22 cm, extending below the diaphragm to the retroperitoneal and intra-abdominal cavity. Contrast enhanced ultrasound showed strong inhomogeneous arterial hyper-enhancement followed by persistent enhancement in a venous phase. Histology obtained with trucut needle biopsy established desmoid tumor, with overall proliferating activity (Ki-67 expression) of 20%. The lesion had been identified as sporadic and unresectable. During the patient’s follow-up a slow but continuous elevation of serum creatinine was registered eventually led to anuria, requiring emergent hemodialysis. The non-obstructing nephropathy is an unusual complication of the disease course, therefore we briefly reviewed the published data on abdominal desmoid tumors and critically analyzed the relation with kidney injury. |
| first_indexed | 2024-12-10T05:01:07Z |
| format | Article |
| id | doaj.art-c195a90c7d5a462bbaf60a2483f61763 |
| institution | Directory Open Access Journal |
| issn | 2036-7414 2036-7422 |
| language | English |
| last_indexed | 2024-12-10T05:01:07Z |
| publishDate | 2018-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastroenterology Insights |
| spelling | doaj.art-c195a90c7d5a462bbaf60a2483f617632022-12-22T02:01:24ZengMDPI AGGastroenterology Insights2036-74142036-74222018-07-019110.4081/gi.2017.6665Desmoid abdominal tumour: A clinical case report and brief literature reviewIrina Ivanova0Shahswar Arif1Dinko Dinev2Kalin Kalchev3Maria Atanassova4Iskren Kotzev5Clinic of Gastroenterology, Department of Internal Diseases, St. Marina Hospital, VarnaMedical University “Dr. Paraskev Stoyanov”, VarnaClinic of Gastroenterology, Department of Internal Diseases, St. Marina Hospital, VarnaDepartment of Pathology, St. Marina Hospital, VarnaClinic of Gastroenterology, Department of Internal Diseases, St. Marina Hospital, VarnaClinic of Gastroenterology, Department of Internal Diseases, St. Marina Hospital, VarnaDesmoid tumors are unique mesenchymal neoplasm. They are able to spread to proximal tissues but tend not to metastasize. Our case presents a 66-year-old female referred for evaluation of the prominent, palpable mass located into the left abdomen. Imaging studies revealed a tumor up to 22 cm, extending below the diaphragm to the retroperitoneal and intra-abdominal cavity. Contrast enhanced ultrasound showed strong inhomogeneous arterial hyper-enhancement followed by persistent enhancement in a venous phase. Histology obtained with trucut needle biopsy established desmoid tumor, with overall proliferating activity (Ki-67 expression) of 20%. The lesion had been identified as sporadic and unresectable. During the patient’s follow-up a slow but continuous elevation of serum creatinine was registered eventually led to anuria, requiring emergent hemodialysis. The non-obstructing nephropathy is an unusual complication of the disease course, therefore we briefly reviewed the published data on abdominal desmoid tumors and critically analyzed the relation with kidney injury.https://www.pagepress.org/journals/index.php/gi/article/view/6665desmoid tumourabdominal neoplasmcontrast enhanced ultrasoundnephropathy |
| spellingShingle | Irina Ivanova Shahswar Arif Dinko Dinev Kalin Kalchev Maria Atanassova Iskren Kotzev Desmoid abdominal tumour: A clinical case report and brief literature review Gastroenterology Insights desmoid tumour abdominal neoplasm contrast enhanced ultrasound nephropathy |
| title | Desmoid abdominal tumour: A clinical case report and brief literature review |
| title_full | Desmoid abdominal tumour: A clinical case report and brief literature review |
| title_fullStr | Desmoid abdominal tumour: A clinical case report and brief literature review |
| title_full_unstemmed | Desmoid abdominal tumour: A clinical case report and brief literature review |
| title_short | Desmoid abdominal tumour: A clinical case report and brief literature review |
| title_sort | desmoid abdominal tumour a clinical case report and brief literature review |
| topic | desmoid tumour abdominal neoplasm contrast enhanced ultrasound nephropathy |
| url | https://www.pagepress.org/journals/index.php/gi/article/view/6665 |
| work_keys_str_mv | AT irinaivanova desmoidabdominaltumouraclinicalcasereportandbriefliteraturereview AT shahswararif desmoidabdominaltumouraclinicalcasereportandbriefliteraturereview AT dinkodinev desmoidabdominaltumouraclinicalcasereportandbriefliteraturereview AT kalinkalchev desmoidabdominaltumouraclinicalcasereportandbriefliteraturereview AT mariaatanassova desmoidabdominaltumouraclinicalcasereportandbriefliteraturereview AT iskrenkotzev desmoidabdominaltumouraclinicalcasereportandbriefliteraturereview |