Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center
We attempt to describe the determinants and outcome of severe soft tissue infections affecting the eye (peri-orbital necrotizing fasciitis or PNF), a rare entity caused by toxin-producing, virulent bacteria. Our series of six adult cases of PNF included patients with and without co-morbidities. Mino...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Clinical Ophthalmology and Research |
| Subjects: | |
| Online Access: | http://www.jcor.in/article.asp?issn=2320-3897;year=2014;volume=2;issue=3;spage=145;epage=148;aulast=Prabhu |
| _version_ | 1828768866221686784 |
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| author | Padma B Prabhu Raju Kuzhupally Vallon |
| author_facet | Padma B Prabhu Raju Kuzhupally Vallon |
| author_sort | Padma B Prabhu |
| collection | DOAJ |
| description | We attempt to describe the determinants and outcome of severe soft tissue infections affecting the eye (peri-orbital necrotizing fasciitis or PNF), a rare entity caused by toxin-producing, virulent bacteria. Our series of six adult cases of PNF included patients with and without co-morbidities. Minor trauma and adjacent focus of infection preceded the development of PNF in four cases. No source of infection could be identified in two patients. Patients with no apparent co-morbidities recovered rapidly with aggressive antibiotic therapy and surgical debridement. However, all the patients who had associated co-morbidities showed a protracted course, two of them with complications. Surprisingly, in majority (5 out of 6), culture grew group A beta-hemolytic streptococcus. Thus, our case series points to the importance of early detection and aggressive treatment of associated co-morbid conditions to avoid complications of this life-threatening, yet treatable disease. |
| first_indexed | 2024-12-11T13:37:24Z |
| format | Article |
| id | doaj.art-c196ed1e84e44c08b9c7e37589167072 |
| institution | Directory Open Access Journal |
| issn | 2320-3897 |
| language | English |
| last_indexed | 2024-12-11T13:37:24Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical Ophthalmology and Research |
| spelling | doaj.art-c196ed1e84e44c08b9c7e375891670722022-12-22T01:04:57ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972014-01-012314514810.4103/2320-3897.138858Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care centerPadma B PrabhuRaju Kuzhupally VallonWe attempt to describe the determinants and outcome of severe soft tissue infections affecting the eye (peri-orbital necrotizing fasciitis or PNF), a rare entity caused by toxin-producing, virulent bacteria. Our series of six adult cases of PNF included patients with and without co-morbidities. Minor trauma and adjacent focus of infection preceded the development of PNF in four cases. No source of infection could be identified in two patients. Patients with no apparent co-morbidities recovered rapidly with aggressive antibiotic therapy and surgical debridement. However, all the patients who had associated co-morbidities showed a protracted course, two of them with complications. Surprisingly, in majority (5 out of 6), culture grew group A beta-hemolytic streptococcus. Thus, our case series points to the importance of early detection and aggressive treatment of associated co-morbid conditions to avoid complications of this life-threatening, yet treatable disease.http://www.jcor.in/article.asp?issn=2320-3897;year=2014;volume=2;issue=3;spage=145;epage=148;aulast=PrabhuDebridementfasciotomynecrosisnecrotizing fasciitispalpebro-orbital |
| spellingShingle | Padma B Prabhu Raju Kuzhupally Vallon Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center Journal of Clinical Ophthalmology and Research Debridement fasciotomy necrosis necrotizing fasciitis palpebro-orbital |
| title | Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center |
| title_full | Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center |
| title_fullStr | Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center |
| title_full_unstemmed | Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center |
| title_short | Determinants and outcome of peri-orbital necrotizing fasciitis: Experience from a tertiary care center |
| title_sort | determinants and outcome of peri orbital necrotizing fasciitis experience from a tertiary care center |
| topic | Debridement fasciotomy necrosis necrotizing fasciitis palpebro-orbital |
| url | http://www.jcor.in/article.asp?issn=2320-3897;year=2014;volume=2;issue=3;spage=145;epage=148;aulast=Prabhu |
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