Collateral activity of the CRISPR/RfxCas13d system in human cells
The collateral activity of the CRISPR/RfxCas13d system in mammalian cells is explored using spike-in RNA-seq and reporter assays.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04708-2 |
| _version_ | 1797853674010050560 |
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| author | Peiguo Shi Michael R. Murphy Alexis O. Aparicio Jordan S. Kesner Zhou Fang Ziheng Chen Aditi Trehan Yang Guo Xuebing Wu |
| author_facet | Peiguo Shi Michael R. Murphy Alexis O. Aparicio Jordan S. Kesner Zhou Fang Ziheng Chen Aditi Trehan Yang Guo Xuebing Wu |
| author_sort | Peiguo Shi |
| collection | DOAJ |
| description | The collateral activity of the CRISPR/RfxCas13d system in mammalian cells is explored using spike-in RNA-seq and reporter assays. |
| first_indexed | 2024-04-09T19:53:28Z |
| format | Article |
| id | doaj.art-c1996c14bbe24db882495b5a23b2c9a7 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T19:53:28Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-c1996c14bbe24db882495b5a23b2c9a72023-04-03T05:36:23ZengNature PortfolioCommunications Biology2399-36422023-03-01611810.1038/s42003-023-04708-2Collateral activity of the CRISPR/RfxCas13d system in human cellsPeiguo Shi0Michael R. Murphy1Alexis O. Aparicio2Jordan S. Kesner3Zhou Fang4Ziheng Chen5Aditi Trehan6Yang Guo7Xuebing Wu8Department of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterDepartment of Medicine and Department of Systems Biology, Columbia University Irving Medical CenterThe collateral activity of the CRISPR/RfxCas13d system in mammalian cells is explored using spike-in RNA-seq and reporter assays.https://doi.org/10.1038/s42003-023-04708-2 |
| spellingShingle | Peiguo Shi Michael R. Murphy Alexis O. Aparicio Jordan S. Kesner Zhou Fang Ziheng Chen Aditi Trehan Yang Guo Xuebing Wu Collateral activity of the CRISPR/RfxCas13d system in human cells Communications Biology |
| title | Collateral activity of the CRISPR/RfxCas13d system in human cells |
| title_full | Collateral activity of the CRISPR/RfxCas13d system in human cells |
| title_fullStr | Collateral activity of the CRISPR/RfxCas13d system in human cells |
| title_full_unstemmed | Collateral activity of the CRISPR/RfxCas13d system in human cells |
| title_short | Collateral activity of the CRISPR/RfxCas13d system in human cells |
| title_sort | collateral activity of the crispr rfxcas13d system in human cells |
| url | https://doi.org/10.1038/s42003-023-04708-2 |
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