CD44s-activated tPA/LRP1-NFκB pathway drives lamellipodia outgrowth in luminal-type breast cancer cells

CD44s-activated tPA/LRP1-NFκB pathway drives lamellipodia outgrowth in luminal-type breast cancer cells

Some cancer cells migration and metastasis are characterized by the outgrowth of lamellipodia protrusions in which the underlying mechanism remains unclear. Evidence has confirmed that lamellipodia formation could be regulated by various adhesion molecules, such as CD44, and we previously reported t...

Full description

Bibliographic Details
Main Authors: Yaqi Qiu, Hui Wang, Qian Guo, Yiwen Liu, Yiqing He, Guoliang Zhang, Cuixia Yang, Yan Du, Feng Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CD44
TPA
lamellipodia
luminal type breast cancer
LRP1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1224827/full

Similar Items

Similar Items