A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption
<p><strong>BACKGROUND</strong>: This study was performed to evaluate the effects of psyllium on kinetics of alimentary carbohydrate absorption in diet-treated type 2 diabetic patients.<br /><strong>METHODS</strong>:...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2007-07-01
|
| Series: | Journal of Research in Medical Sciences |
| Subjects: | |
| Online Access: | http://journals.mui.ac.ir/jrms/article/view/576 |
| _version_ | 1818524705436467200 |
|---|---|
| author | Mansour Siavash Maryam Salehioun Alireza Najafian Masoud Amini |
| author_facet | Mansour Siavash Maryam Salehioun Alireza Najafian Masoud Amini |
| author_sort | Mansour Siavash |
| collection | DOAJ |
| description | <p><strong>BACKGROUND</strong>: This study was performed to evaluate the effects of psyllium on kinetics of alimentary carbohydrate absorption in diet-treated type 2 diabetic patients.<br /><strong>METHODS</strong>: This was a double blind, prospective, controlled clinical trial. Twelve patients (6 in each group) participated in the present study. After an overnight fast, a standard 435 kcal breakfast was given to participants. Fasting, 1- and 2- hour postprandial plasma glucose was measured in the case and control groups. Cow&rsquo;s milk containing 5 grams of psyllium granules for the case and without psyllium for the control groups was also delivered.<br /><strong>RESULTS</strong>: Plasma glucose changes in the first hour were significantly different between control and case groups (53.8 versus 17.8 respectively, P = 0.037). Also, mean 2-hour postprandial plasma glucose was 167.67 and 117.67 mg/dl for control and case groups, respectively (P = 0.05).<br /><strong>CONCLUSIONS</strong>: This pilot study revealed that psyllium may effectively reduce postprandial plasma glucose possibly by retarding GI carbohydrate absorption. Larger studies are needed to confirm the results of this study and define its role compared to acarbose or meglitinides.<br /><strong>KEYWORDS</strong>: Psyllium, postprandial hyperglycemia, type 2 diabetes mellitus.</p> |
| first_indexed | 2024-12-11T06:00:26Z |
| format | Article |
| id | doaj.art-c19efc260619408d99de17a4b1e87d99 |
| institution | Directory Open Access Journal |
| issn | 1735-1995 1735-7136 |
| language | English |
| last_indexed | 2024-12-11T06:00:26Z |
| publishDate | 2007-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Medical Sciences |
| spelling | doaj.art-c19efc260619408d99de17a4b1e87d992022-12-22T01:18:30ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362007-07-01123125130A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorptionMansour SiavashMaryam SalehiounAlireza NajafianMasoud Amini<p><strong>BACKGROUND</strong>: This study was performed to evaluate the effects of psyllium on kinetics of alimentary carbohydrate absorption in diet-treated type 2 diabetic patients.<br /><strong>METHODS</strong>: This was a double blind, prospective, controlled clinical trial. Twelve patients (6 in each group) participated in the present study. After an overnight fast, a standard 435 kcal breakfast was given to participants. Fasting, 1- and 2- hour postprandial plasma glucose was measured in the case and control groups. Cow&rsquo;s milk containing 5 grams of psyllium granules for the case and without psyllium for the control groups was also delivered.<br /><strong>RESULTS</strong>: Plasma glucose changes in the first hour were significantly different between control and case groups (53.8 versus 17.8 respectively, P = 0.037). Also, mean 2-hour postprandial plasma glucose was 167.67 and 117.67 mg/dl for control and case groups, respectively (P = 0.05).<br /><strong>CONCLUSIONS</strong>: This pilot study revealed that psyllium may effectively reduce postprandial plasma glucose possibly by retarding GI carbohydrate absorption. Larger studies are needed to confirm the results of this study and define its role compared to acarbose or meglitinides.<br /><strong>KEYWORDS</strong>: Psyllium, postprandial hyperglycemia, type 2 diabetes mellitus.</p>http://journals.mui.ac.ir/jrms/article/view/576Psyllium, postprandial hyperglycemia, type 2 diabetes mellitus |
| spellingShingle | Mansour Siavash Maryam Salehioun Alireza Najafian Masoud Amini A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption Journal of Research in Medical Sciences Psyllium, postprandial hyperglycemia, type 2 diabetes mellitus |
| title | A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption |
| title_full | A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption |
| title_fullStr | A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption |
| title_full_unstemmed | A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption |
| title_short | A randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption |
| title_sort | randomized controlled study for evaluation of psyllium effects on kinetics of carbohydrate absorption |
| topic | Psyllium, postprandial hyperglycemia, type 2 diabetes mellitus |
| url | http://journals.mui.ac.ir/jrms/article/view/576 |
| work_keys_str_mv | AT mansoursiavash arandomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT maryamsalehioun arandomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT alirezanajafian arandomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT masoudamini arandomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT mansoursiavash randomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT maryamsalehioun randomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT alirezanajafian randomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption AT masoudamini randomizedcontrolledstudyforevaluationofpsylliumeffectsonkineticsofcarbohydrateabsorption |