Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Abstract Background Efforts to improve animal health, and understand genetic bases for production, may benefit from a comprehensive analysis of animal genomes and epigenomes. Although DNA methylation has been well studied in humans and other model species, its distribution patterns and regulatory im...

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Bibliographic Details
Main Authors: Yang Zhou, Shuli Liu, Yan Hu, Lingzhao Fang, Yahui Gao, Han Xia, Steven G. Schroeder, Benjamin D. Rosen, Erin E. Connor, Cong-jun Li, Ransom L. Baldwin, John B. Cole, Curtis P. Van Tassell, Liguo Yang, Li Ma, George E. Liu
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Biology
Subjects:
Cattle
Somatic tissues
DNA methylation
Partially methylated domains
Hypomethylated region
WGBS (whole genome bisulfite sequencing)
Online Access:http://link.springer.com/article/10.1186/s12915-020-00793-5

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http://link.springer.com/article/10.1186/s12915-020-00793-5

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