Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study
Background: Chronic venous leg ulcers are difficult to treat and recurrences are common. Among various modalities of treatment, platelet-rich fibrin (PRF) has shown promising results in ulcer healing by providing necessary growth factors. Unna's paste dressing has also proven to enhance wound h...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Dermatology Online Journal |
| Subjects: | |
| Online Access: | http://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=1;spage=58;epage=61;aulast=Yuvasri |
| _version_ | 1819153888293421056 |
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| author | G Yuvasri Reena Rai |
| author_facet | G Yuvasri Reena Rai |
| author_sort | G Yuvasri |
| collection | DOAJ |
| description | Background: Chronic venous leg ulcers are difficult to treat and recurrences are common. Among various modalities of treatment, platelet-rich fibrin (PRF) has shown promising results in ulcer healing by providing necessary growth factors. Unna's paste dressing has also proven to enhance wound healing. Aim: The aim of this study is to compare the efficacy of autologous PRF versus Unna's paste dressing in chronic venous leg ulcer patients and to compare the mean reduction in ulcer area at the end of 4 weeks. Materials and Methods: Twenty patients with chronic venous leg ulcers were randomly divided into two groups. Group 1: Patients received PRF dressing which was repeated every week for 4 weeks. Group 2: Patients received Unna's paste dressing once a week for 4 weeks. The ulcer size was assessed with the help of photographs, and ulcer area was measured. Results: The mean reduction in the area of the ulcer size in the PRF group was 86.03% and in the Unna's paste group was 71.97%, which was not statistically significant with a P value of 0.223. Conclusion: We conclude that though there was no statistical significance between the groups, PRF showed a significant reduction in ulcer size. |
| first_indexed | 2024-12-22T15:12:20Z |
| format | Article |
| id | doaj.art-c1a1b1182b3f4855829ae4939783a267 |
| institution | Directory Open Access Journal |
| issn | 2229-5178 |
| language | English |
| last_indexed | 2024-12-22T15:12:20Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Dermatology Online Journal |
| spelling | doaj.art-c1a1b1182b3f4855829ae4939783a2672022-12-21T18:21:50ZengWolters Kluwer Medknow PublicationsIndian Dermatology Online Journal2229-51782020-01-01111586110.4103/idoj.IDOJ_119_19Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative studyG YuvasriReena RaiBackground: Chronic venous leg ulcers are difficult to treat and recurrences are common. Among various modalities of treatment, platelet-rich fibrin (PRF) has shown promising results in ulcer healing by providing necessary growth factors. Unna's paste dressing has also proven to enhance wound healing. Aim: The aim of this study is to compare the efficacy of autologous PRF versus Unna's paste dressing in chronic venous leg ulcer patients and to compare the mean reduction in ulcer area at the end of 4 weeks. Materials and Methods: Twenty patients with chronic venous leg ulcers were randomly divided into two groups. Group 1: Patients received PRF dressing which was repeated every week for 4 weeks. Group 2: Patients received Unna's paste dressing once a week for 4 weeks. The ulcer size was assessed with the help of photographs, and ulcer area was measured. Results: The mean reduction in the area of the ulcer size in the PRF group was 86.03% and in the Unna's paste group was 71.97%, which was not statistically significant with a P value of 0.223. Conclusion: We conclude that though there was no statistical significance between the groups, PRF showed a significant reduction in ulcer size.http://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=1;spage=58;epage=61;aulast=Yuvasriplatelet-rich fibrinunna's pastevenous leg ulcer |
| spellingShingle | G Yuvasri Reena Rai Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study Indian Dermatology Online Journal platelet-rich fibrin unna's paste venous leg ulcer |
| title | Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study |
| title_full | Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study |
| title_fullStr | Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study |
| title_full_unstemmed | Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study |
| title_short | Comparison of efficacy of autologous platelet-rich fibrin versus Unna's paste dressing in chronic venous leg ulcers: A comparative study |
| title_sort | comparison of efficacy of autologous platelet rich fibrin versus unna s paste dressing in chronic venous leg ulcers a comparative study |
| topic | platelet-rich fibrin unna's paste venous leg ulcer |
| url | http://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=1;spage=58;epage=61;aulast=Yuvasri |
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