A study on pediatric respiratory tract infections in hospitalised children from Chennai

A study on pediatric respiratory tract infections in hospitalised children from Chennai

Globally, acute respiratory tract infections (ARTIs) are the leading cause of childhood morbidity and mortality. However, these infections remain poorly understood due to absence of affordable and effective diagnostic tools. In this study, viral acute respiratory tract infections were studied in hos...

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Bibliographic Details
Main Authors: Sara Chandy, Anand Manoharan, Abdul Hameed, Lionel Kumar Jones, Gothai S Nachiyar, M.S. Ramya, Amullya Sudhakar, Sumanth A, S. Balasubramanian
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Clinical Epidemiology and Global Health
Subjects:
Viral agents
Pediatric ARTI
Multiplexed real time RT-PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2213398422001099
Description
Summary:Globally, acute respiratory tract infections (ARTIs) are the leading cause of childhood morbidity and mortality. However, these infections remain poorly understood due to absence of affordable and effective diagnostic tools. In this study, viral acute respiratory tract infections were studied in hospitalised children up to 5 years of age (n = 256) using a commercial multiplex real time PCR. RSV (45.69%%), RV (17.88%), HBoV (7.95%), Influ B (7.28%), HMPV (6.6%), HPIV3 (5.96%) and Influ A virus (3.97%) were the common etiological agents detected. There was no significant correlation between the clinical signs and symptoms in patients with and without a viral aetiology. Multiplexed real time PCR is an important tool for early detection of viral agents of paediatric ARTI.
ISSN:2213-3984

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