Transcriptome and metabolome analysis reveals PRV XJ delgE/gI/TK protects intracranially infected mice from death by regulating the inflammation

Transcriptome and metabolome analysis reveals PRV XJ delgE/gI/TK protects intracranially infected mice from death by regulating the inflammation

Pseudorabies virus can cause inflammation in the central nervous system and neurological symptoms. To further investigate the protective mechanism of PRV XJ delgE/gI/TK in the central nervous system, an intracranial PRV-infection mice model was developed. The results demonstrated that immunization w...

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Bibliographic Details
Main Authors: Lei Xu, Yang Zhang, Qian Tao, Tong Xu, Feng-qin Lee, Li-shuang Deng, Zhijie Jian, Jun Zhao, Yanting Yang, Siyuan Lai, Yuan-cheng Zhou, Zhi-wen Xu, Ling Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
pseudorabies virus
inflammation
intracranial infection
transcriptome
metabolome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1374646/full

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