EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS
The aim of the study was to relieve the effect of synthesis product (by-product of salicylic acid) administration 5-cloro-2hidroxy-azotil-sulfamoil-fenil benzamide (5ClSA-SA) in comparison with basic structural compounds (salicylamide and sulfanilamide) on some parameters of proteic metabolism on ra...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Agroprint Timisoara
2023-11-01
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| Series: | Scientific Papers Animal Science and Biotechnologies |
| Subjects: | |
| Online Access: | https://spasb.ro/index.php/public_html/article/view/1918 |
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| author | LETIŢIA STANA ALEXANDRA TRIF LOREDANA GABRIELA STANA ALFA XENIA LUPEA MIRABELA PĂDURE F. MUSELIN |
| author_facet | LETIŢIA STANA ALEXANDRA TRIF LOREDANA GABRIELA STANA ALFA XENIA LUPEA MIRABELA PĂDURE F. MUSELIN |
| author_sort | LETIŢIA STANA |
| collection | DOAJ |
| description | The aim of the study was to relieve the effect of synthesis product (by-product of
salicylic acid) administration 5-cloro-2hidroxy-azotil-sulfamoil-fenil benzamide
(5ClSA-SA) in comparison with basic structural compounds (salicylamide and
sulfanilamide) on some parameters of proteic metabolism on rats. The synthesis
product 5ClSA-SA is amide of 5 chlorosalycilic acid with sulfanilamide synthesized
at The Technical University, Faculty of Industrial Chemistry of Timisoara. The
experimental results demonstrate that the synthesis product has determinate a strong
significant increase (p<0.01) of proteinemia compared to test, over the physiological
limits; salicylamide has induces the significant increase (p<0.05), and sulfanilamide
has induced the significant decrease (p<0.05) of total proteins compared to test but
in physiological limits. After the administration of the three substances, the albumin
and urea values has strong significant decrease (p<0.01) compared to test and under
the physiological limits. The synthesis product has not determinate significant
differences (p>0.05) of creatinine compared to test, obtained values being situated in
physiological limits, while salicylamide and sulfanilamide have induced strong
significant decrease (p>0.01), respectively significant (p>0.05) compared to test and
under physiological limits. |
| first_indexed | 2024-04-24T13:42:07Z |
| format | Article |
| id | doaj.art-c1a38bfdfdd14252a6c625437fd34559 |
| institution | Directory Open Access Journal |
| issn | 1841-9364 2344-4576 |
| language | English |
| last_indexed | 2024-04-24T13:42:07Z |
| publishDate | 2023-11-01 |
| publisher | Agroprint Timisoara |
| record_format | Article |
| series | Scientific Papers Animal Science and Biotechnologies |
| spelling | doaj.art-c1a38bfdfdd14252a6c625437fd345592024-04-04T07:47:43ZengAgroprint TimisoaraScientific Papers Animal Science and Biotechnologies1841-93642344-45762023-11-014117987981918EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATSLETIŢIA STANA0ALEXANDRA TRIF1LOREDANA GABRIELA STANA2ALFA XENIA LUPEA3MIRABELA PĂDURE4F. MUSELIN5Faculty of Veterinary Medicine Timişoara, Romania, Faculty of Veterinary Medicine Timişoara, Romania, University of Medicine and Pharmacy, Timişoara, RomaniIa, Industrial Chemistry and Environmental Engineering Faculty, Timişoara, Romania Industrial Chemistry and Environmental Engineering Faculty, Timişoara, Romania Faculty of Veterinary Medicine Timişoara, Romania, The aim of the study was to relieve the effect of synthesis product (by-product of salicylic acid) administration 5-cloro-2hidroxy-azotil-sulfamoil-fenil benzamide (5ClSA-SA) in comparison with basic structural compounds (salicylamide and sulfanilamide) on some parameters of proteic metabolism on rats. The synthesis product 5ClSA-SA is amide of 5 chlorosalycilic acid with sulfanilamide synthesized at The Technical University, Faculty of Industrial Chemistry of Timisoara. The experimental results demonstrate that the synthesis product has determinate a strong significant increase (p<0.01) of proteinemia compared to test, over the physiological limits; salicylamide has induces the significant increase (p<0.05), and sulfanilamide has induced the significant decrease (p<0.05) of total proteins compared to test but in physiological limits. After the administration of the three substances, the albumin and urea values has strong significant decrease (p<0.01) compared to test and under the physiological limits. The synthesis product has not determinate significant differences (p>0.05) of creatinine compared to test, obtained values being situated in physiological limits, while salicylamide and sulfanilamide have induced strong significant decrease (p>0.01), respectively significant (p>0.05) compared to test and under physiological limits.https://spasb.ro/index.php/public_html/article/view/1918proteinalbuminureacreatininerat |
| spellingShingle | LETIŢIA STANA ALEXANDRA TRIF LOREDANA GABRIELA STANA ALFA XENIA LUPEA MIRABELA PĂDURE F. MUSELIN EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS Scientific Papers Animal Science and Biotechnologies protein albumin urea creatinine rat |
| title | EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS |
| title_full | EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS |
| title_fullStr | EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS |
| title_full_unstemmed | EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS |
| title_short | EFFECT OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID) IN COMPARISON WITH BASIS STRUCTURAL COMPOUNDS ON SOME PROTEIC METABOLISM PARAMETERS IN RATS |
| title_sort | effect of a synthesis product by product of salicylic acid in comparison with basis structural compounds on some proteic metabolism parameters in rats |
| topic | protein albumin urea creatinine rat |
| url | https://spasb.ro/index.php/public_html/article/view/1918 |
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