Urolithins Modulate the Viability, Autophagy, Apoptosis, and Nephrin Turnover in Podocytes Exposed to High Glucose

Urolithins Modulate the Viability, Autophagy, Apoptosis, and Nephrin Turnover in Podocytes Exposed to High Glucose

Urolithins are bioactive compounds generated in human and animal intestines because of the bacterial metabolism of dietary ellagitannins (and their constituent, ellagic acid). Due to their multidirectional effects, including anti-inflammatory, antioxidant, anti-cancer, neuroprotective, and antiglyca...

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Bibliographic Details
Main Authors: Milena Kotewicz, Mirosława Krauze-Baranowska, Agnieszka Daca, Agata Płoska, Sylwia Godlewska, Leszek Kalinowski, Barbara Lewko
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
podocytes
urolithins
urolithin A
high glucose
nephrin
diabetic nephropathy
Online Access:https://www.mdpi.com/2073-4409/11/16/2471

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