Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies
Aim: The aim of this study was to compare the resistance to asymptomatic bacteriuria (ABU) between term and preterm pregnancies. Material and Methods: Pregnant women aged 17-41 years who were followed up in the obstetrics department of our hospital and whose urine cultures were sent to the laborator...
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| Format: | Article |
| Language: | English |
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Duzce University
2022-12-01
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| Series: | Düzce Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/download/article-file/2603429 |
| _version_ | 1797426430359896064 |
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| author | Reyhan Ayaz İhsan Ayhan Ahmet Naci Emecen Pinar Ergen Damla Dökmeci Güney Özlem Aydın |
| author_facet | Reyhan Ayaz İhsan Ayhan Ahmet Naci Emecen Pinar Ergen Damla Dökmeci Güney Özlem Aydın |
| author_sort | Reyhan Ayaz |
| collection | DOAJ |
| description | Aim: The aim of this study was to compare the resistance to asymptomatic bacteriuria (ABU) between term and preterm pregnancies.
Material and Methods: Pregnant women aged 17-41 years who were followed up in the obstetrics department of our hospital and whose urine cultures were sent to the laboratory for analysis and reported as ABU were included in the study. Patients were divided into two groups according to gestational weeks as preterm (<37 weeks) and term (≥37 weeks). The results were compared between the two groups.
Results: From among a total of 123 pregnant women, 29 (23.6%) delivered at preterm and 94 (76.4%) at term. The most frequently identified pathogen throughout the study group was 52.0% (n=64) Escherichia coli (E. coli), followed by 16.3% (n=20) Streptococcus agalactiae (S. agalactiae). There was no statistically significant difference in terms of the distribution of E. coli and S. agalactiae between the term and preterm groups (p=0.698 and p=0.930). E. coli was resistant to ampicillin 56.3% (n=36), to cefuroxime 40.6% (n=26). While fosfomycin resistance was 1.6% (n=1), nitrofurantoin resistance was not found. Extended-spectrum beta-lactamase positivity was 23.4% (n=15) in E. coli strains. No statistically significant difference was found in antibiotic resistance rates of E. coli strains between the term and preterm groups.
Conclusion: The most commonly isolated pathogen was E. coli which was highly resistant to beta-lactams. Screening of pregnant women for ABU and treatment with appropriate antibiotics; is the most effective way to prevent both maternal and fetal complications and antimicrobial resistance. |
| first_indexed | 2024-03-09T08:30:05Z |
| format | Article |
| id | doaj.art-c1ab5684eff046b8b415b46d2d0de67b |
| institution | Directory Open Access Journal |
| issn | 1307-671X |
| language | English |
| last_indexed | 2024-03-09T08:30:05Z |
| publishDate | 2022-12-01 |
| publisher | Duzce University |
| record_format | Article |
| series | Düzce Tıp Fakültesi Dergisi |
| spelling | doaj.art-c1ab5684eff046b8b415b46d2d0de67b2023-12-02T20:23:56ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2022-12-0124324725110.18678/dtfd.116377097Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm PregnanciesReyhan Ayaz0İhsan Ayhan1Ahmet Naci Emecen2Pinar Ergen3Damla Dökmeci Güney4Özlem Aydın5İstanbul Göztepe Prof. Dr. Süleyman Yalçın Şehir HastanesiZonguldak Atatürk Devlet HastanesiDOKUZ EYLÜL ÜNİVERSİTESİİstanbul Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesiİstanbul Göztepe Prof. Dr. Süleyman Yalçın Şehir HastanesiMedeniyet Üniversitesi Göztepe Eğitim Araştırma HastanesiAim: The aim of this study was to compare the resistance to asymptomatic bacteriuria (ABU) between term and preterm pregnancies. Material and Methods: Pregnant women aged 17-41 years who were followed up in the obstetrics department of our hospital and whose urine cultures were sent to the laboratory for analysis and reported as ABU were included in the study. Patients were divided into two groups according to gestational weeks as preterm (<37 weeks) and term (≥37 weeks). The results were compared between the two groups. Results: From among a total of 123 pregnant women, 29 (23.6%) delivered at preterm and 94 (76.4%) at term. The most frequently identified pathogen throughout the study group was 52.0% (n=64) Escherichia coli (E. coli), followed by 16.3% (n=20) Streptococcus agalactiae (S. agalactiae). There was no statistically significant difference in terms of the distribution of E. coli and S. agalactiae between the term and preterm groups (p=0.698 and p=0.930). E. coli was resistant to ampicillin 56.3% (n=36), to cefuroxime 40.6% (n=26). While fosfomycin resistance was 1.6% (n=1), nitrofurantoin resistance was not found. Extended-spectrum beta-lactamase positivity was 23.4% (n=15) in E. coli strains. No statistically significant difference was found in antibiotic resistance rates of E. coli strains between the term and preterm groups. Conclusion: The most commonly isolated pathogen was E. coli which was highly resistant to beta-lactams. Screening of pregnant women for ABU and treatment with appropriate antibiotics; is the most effective way to prevent both maternal and fetal complications and antimicrobial resistance.https://dergipark.org.tr/en/download/article-file/2603429gebelikasemptomatik bakteriüriantibiyotik direncipregnancyasymptomatic bacteriuriaantibiotic resistance |
| spellingShingle | Reyhan Ayaz İhsan Ayhan Ahmet Naci Emecen Pinar Ergen Damla Dökmeci Güney Özlem Aydın Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies Düzce Tıp Fakültesi Dergisi gebelik asemptomatik bakteriüri antibiyotik direnci pregnancy asymptomatic bacteriuria antibiotic resistance |
| title | Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies |
| title_full | Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies |
| title_fullStr | Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies |
| title_full_unstemmed | Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies |
| title_short | Comparison of Asymptomatic Bacteriuria Agents and Antimicrobial Susceptibility in Term and Preterm Pregnancies |
| title_sort | comparison of asymptomatic bacteriuria agents and antimicrobial susceptibility in term and preterm pregnancies |
| topic | gebelik asemptomatik bakteriüri antibiyotik direnci pregnancy asymptomatic bacteriuria antibiotic resistance |
| url | https://dergipark.org.tr/en/download/article-file/2603429 |
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