Orexin A and Orexin Receptor 1 axonal traffic in dorsal roots at the CNS/PNS interface

Orexin A and Orexin Receptor 1 axonal traffic in dorsal roots at the CNS/PNS interface

Hypothalamic orexin/hypocretin neurons send long axonal projections through the dorsal spinal cord in lamina I-II of the dorsal horn at the interface with the peripheral nervous system (PNS). We show that in the dorsal horn OXA fibers colocalize with substance P (SP) positive afferents of dorsal roo...

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Bibliographic Details
Main Authors: Damien eColas, Annalisa eManca, Jean-Dominique eDelcroix, Philippe eMourrain
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Neuroscience
Subjects:
Axonal Transport
Nociception
Substance P
dorsal root ganglia
hypocretin
orexin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00020/full

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