Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

<p>Abstract</p> <p>Background</p> <p>In our previous study, we detected decreased expression of phospho-Smad1/5/8 and its upstream signaling molecule, bone morphogenetic protein receptor IB subunit (BMPR-IB), in certain glioblastoma tissues, unlike normal brain tissues....

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Bibliographic Details
Main Authors: Liu Shuang, Yin Feng, Fan Wenhong, Wang Shuwei, Guo Xin-ru, Zhang Jian-ning, Tian Zeng-min, Fan Ming
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
1. BMPR-IB
2. Glioblastoma
3. Growth inhibition
4. Differentiation
Online Access:http://www.jeccr.com/content/31/1/52

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