CLEC19A overexpression inhibits tumor cell proliferation/migration and promotes apoptosis concomitant suppression of PI3K/AKT/NF-κB signaling pathway in glioblastoma multiforme
Abstract Background GBM is the most frequent malignant primary brain tumor in humans. The CLEC19A is a member of the C-type lectin family, which has a high expression in brain tissue. Herein, we sought to carry out an in-depth analysis to pinpoint the role of CLEC19A expression in GBM. Methods To de...
Main Authors: | Fatemeh Mohajerani, Zahra Moazezi Tehrankhah, Saeid Rahmani, Nastaran Afsordeh, Sajad Shafiee, Mohammad Hossein Pourgholami, Bahram M. Soltani, Majid Sadeghizadeh |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-023-11755-9 |
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