Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo

Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo

Summary: Mitochondrial Ca2+ uptake is an important mediator of metabolism and cell death. Identification of components of the highly conserved mitochondrial Ca2+ uniporter has opened it up to genetic analysis in model organisms. Here, we report a comprehensive genetic characterization of all known u...

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Bibliographic Details
Main Authors:	Roberta Tufi, Thomas P. Gleeson, Sophia von Stockum, Victoria L. Hewitt, Juliette J. Lee, Ana Terriente-Felix, Alvaro Sanchez-Martinez, Elena Ziviani, Alexander J. Whitworth
Format:	Article
Language:	English
Published:	Elsevier 2019-04-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S221112471930498X

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