A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops

Cardiac ventricle function can be measured from a multiple-beat pressure volume loop sequence, or estimated from a single beat of pressure volume loop data. In this study, the effectiveness of single-beat estimation is evaluated with functional markers defined by maximum elastance, isovolumic mode d...

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Main Author: Edward Marcus
Format: Article
Language:English
Published: IFSA Publishing, S.L. 2020-09-01
Series:Sensors & Transducers
Subjects:
Online Access:https://sensorsportal.com/HTML/DIGEST/september_2020/Vol_244/P_3159.pdf
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author Edward Marcus
author_facet Edward Marcus
author_sort Edward Marcus
collection DOAJ
description Cardiac ventricle function can be measured from a multiple-beat pressure volume loop sequence, or estimated from a single beat of pressure volume loop data. In this study, the effectiveness of single-beat estimation is evaluated with functional markers defined by maximum elastance, isovolumic mode developed pressure, ejecting mode pressure volume area, and isovolumic mode pressure volume area. These estimates applied a linear regression model of chamber volume equilibrium as the calculation input. With data collected from 23 published pressure volume diagrams, estimates were assessed for percent differences to multi-beat outcomes. Results by method were: isovolumic pressure volume area (4 ± 4 %), isovolumic peak pressure (8 ± 6 %), ejecting pressure volume area (9 ± 6 %), and maximum elastance (22 ± 17%); p<.0001 one way ANOVA. The isovolumic pressure volume area estimates had the minimum overall error, and appeared to correlate with chamber volume variations through a measured range from 25 mL to 230 mL. This size correlation suggests the method is useful for interpreting normality of natural changes occurring during developmental stages of pediatric patient growth.
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spelling doaj.art-c1bbed462ce34b45b97744cdf2bebc432023-08-02T15:52:09ZengIFSA Publishing, S.L.Sensors & Transducers2306-85151726-54792020-09-01244516A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume LoopsEdward Marcus0Cardiology Department, Children’s Hospital BostonCardiac ventricle function can be measured from a multiple-beat pressure volume loop sequence, or estimated from a single beat of pressure volume loop data. In this study, the effectiveness of single-beat estimation is evaluated with functional markers defined by maximum elastance, isovolumic mode developed pressure, ejecting mode pressure volume area, and isovolumic mode pressure volume area. These estimates applied a linear regression model of chamber volume equilibrium as the calculation input. With data collected from 23 published pressure volume diagrams, estimates were assessed for percent differences to multi-beat outcomes. Results by method were: isovolumic pressure volume area (4 ± 4 %), isovolumic peak pressure (8 ± 6 %), ejecting pressure volume area (9 ± 6 %), and maximum elastance (22 ± 17%); p<.0001 one way ANOVA. The isovolumic pressure volume area estimates had the minimum overall error, and appeared to correlate with chamber volume variations through a measured range from 25 mL to 230 mL. This size correlation suggests the method is useful for interpreting normality of natural changes occurring during developmental stages of pediatric patient growth.https://sensorsportal.com/HTML/DIGEST/september_2020/Vol_244/P_3159.pdfpressure volume loopsingle-beat estimatespressure volume areaisovolumic contracting modecontractility methods
spellingShingle Edward Marcus
A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops
Sensors & Transducers
pressure volume loop
single-beat estimates
pressure volume area
isovolumic contracting mode
contractility methods
title A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops
title_full A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops
title_fullStr A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops
title_full_unstemmed A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops
title_short A Study of Cardiac Ventricle Performance Indices Estimated with Data from Single-Beat Pressure Volume Loops
title_sort study of cardiac ventricle performance indices estimated with data from single beat pressure volume loops
topic pressure volume loop
single-beat estimates
pressure volume area
isovolumic contracting mode
contractility methods
url https://sensorsportal.com/HTML/DIGEST/september_2020/Vol_244/P_3159.pdf
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