Study of abnormal microflora in progression and treatment of Parkinson's disease
Parkinson's disease is the second most common neurodegenerative disease in the elderly population. Recent research provides evidence for the hypothesis of the intestinal origin of Parkinson's disease. Intestinal flora can affect the central nervous system through two-way communication betw...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2023-05-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1686187549801-64847716.pdf |
| _version_ | 1797808903771127808 |
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| author | Yue Xinyi, Zhou Qingbo |
| author_facet | Yue Xinyi, Zhou Qingbo |
| author_sort | Yue Xinyi, Zhou Qingbo |
| collection | DOAJ |
| description | Parkinson's disease is the second most common neurodegenerative disease in the elderly population. Recent research provides evidence for the hypothesis of the intestinal origin of Parkinson's disease. Intestinal flora can affect the central nervous system through two-way communication between the gut and brain. Abnormal microflora plays an important role in Parkinson's disease by causing abnormal aggregation of α-synuclein. Parkinson's disease drugs can interact with intestinal microflora， and specific microflora is related to clinical characteristics of Parkinson's disease. Improving the composition of intestinal microflora can reduce the risk of Parkinson's disease and delay the disease progression. In this article， the pathophysiology， clinical features and treatment of abnormal microflora in Parkinson's disease were reviewed. |
| first_indexed | 2024-03-13T06:44:36Z |
| format | Article |
| id | doaj.art-c1c00c8fe261446889962d2b2218e54a |
| institution | Directory Open Access Journal |
| issn | 0253-9802 |
| language | zho |
| last_indexed | 2024-03-13T06:44:36Z |
| publishDate | 2023-05-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj.art-c1c00c8fe261446889962d2b2218e54a2023-06-08T08:59:10ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022023-05-0154531231610.3969/j.issn.0253-9802.2023.05.002Study of abnormal microflora in progression and treatment of Parkinson's diseaseYue Xinyi, Zhou Qingbo0Cheeloo College of Medicine， Shandong University， Jinan 250012， ChinaParkinson's disease is the second most common neurodegenerative disease in the elderly population. Recent research provides evidence for the hypothesis of the intestinal origin of Parkinson's disease. Intestinal flora can affect the central nervous system through two-way communication between the gut and brain. Abnormal microflora plays an important role in Parkinson's disease by causing abnormal aggregation of α-synuclein. Parkinson's disease drugs can interact with intestinal microflora， and specific microflora is related to clinical characteristics of Parkinson's disease. Improving the composition of intestinal microflora can reduce the risk of Parkinson's disease and delay the disease progression. In this article， the pathophysiology， clinical features and treatment of abnormal microflora in Parkinson's disease were reviewed.https://www.xinyixue.cn/fileup/0253-9802/PDF/1686187549801-64847716.pdf|parkinson's disease|microflora abnormality|α-synuclein |
| spellingShingle | Yue Xinyi, Zhou Qingbo Study of abnormal microflora in progression and treatment of Parkinson's disease Xin yixue |parkinson's disease|microflora abnormality|α-synuclein |
| title | Study of abnormal microflora in progression and treatment of Parkinson's disease |
| title_full | Study of abnormal microflora in progression and treatment of Parkinson's disease |
| title_fullStr | Study of abnormal microflora in progression and treatment of Parkinson's disease |
| title_full_unstemmed | Study of abnormal microflora in progression and treatment of Parkinson's disease |
| title_short | Study of abnormal microflora in progression and treatment of Parkinson's disease |
| title_sort | study of abnormal microflora in progression and treatment of parkinson s disease |
| topic | |parkinson's disease|microflora abnormality|α-synuclein |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1686187549801-64847716.pdf |
| work_keys_str_mv | AT yuexinyizhouqingbo studyofabnormalmicroflorainprogressionandtreatmentofparkinsonsdisease |