Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents

The corona virus disease 2019 (COVID-19) pandemic has till date (26/7/20) affected 1crore 62 lac 73 thousand 638 people globally with almost 6.5 lakh mortalities. COVID-19 has invaded the operation theatre and intensive care unit (ICU) in a short span of 6 months. It appears inevitable that all of u...

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Main Authors: Shagun B Shah, Uma Hariharan, Rajiv Chawla
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2021;volume=37;issue=2;spage=160;epage=170;aulast=Shah
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author Shagun B Shah
Uma Hariharan
Rajiv Chawla
author_facet Shagun B Shah
Uma Hariharan
Rajiv Chawla
author_sort Shagun B Shah
collection DOAJ
description The corona virus disease 2019 (COVID-19) pandemic has till date (26/7/20) affected 1crore 62 lac 73 thousand 638 people globally with almost 6.5 lakh mortalities. COVID-19 has invaded the operation theatre and intensive care unit (ICU) in a short span of 6 months. It appears inevitable that all of us, as anesthesiologists, have to treat COVID-positive patients, either in the ICU or the operation theatre. Many asymptomatic, presumably noninfected people including frontline health care workers are also consuming potential anticorona viral drugs (such as hydroxychloroquine) prophylactically and may present for surgery. Detailed knowledge of which anesthetic and perioperative care drugs can interact with anti-COVID drugs would be very valuable for pre, intra-, and postoperative management of such patients and COVID-19 positive patients requiring intubation, mechanical ventilation, and ICU-sedation. Powered with this knowledge, anesthesiologists and intensivists can minimize the adverse effects of drug interactions. An extensive literature search using different search engines including Cochrane, Embase, Google Scholar, Scopus, and PubMed for all indexed review articles, original articles, case reports, and referenced webpages was performed to extract the most current and relevant literature on drug-drug interactions for clinicians.
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spelling doaj.art-c1c1e54a4639423987984e9fc65c63832022-12-21T18:22:45ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852021-01-0137216017010.4103/joacp.JOACP_461_20Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agentsShagun B ShahUma HariharanRajiv ChawlaThe corona virus disease 2019 (COVID-19) pandemic has till date (26/7/20) affected 1crore 62 lac 73 thousand 638 people globally with almost 6.5 lakh mortalities. COVID-19 has invaded the operation theatre and intensive care unit (ICU) in a short span of 6 months. It appears inevitable that all of us, as anesthesiologists, have to treat COVID-positive patients, either in the ICU or the operation theatre. Many asymptomatic, presumably noninfected people including frontline health care workers are also consuming potential anticorona viral drugs (such as hydroxychloroquine) prophylactically and may present for surgery. Detailed knowledge of which anesthetic and perioperative care drugs can interact with anti-COVID drugs would be very valuable for pre, intra-, and postoperative management of such patients and COVID-19 positive patients requiring intubation, mechanical ventilation, and ICU-sedation. Powered with this knowledge, anesthesiologists and intensivists can minimize the adverse effects of drug interactions. An extensive literature search using different search engines including Cochrane, Embase, Google Scholar, Scopus, and PubMed for all indexed review articles, original articles, case reports, and referenced webpages was performed to extract the most current and relevant literature on drug-drug interactions for clinicians.http://www.joacp.org/article.asp?issn=0970-9185;year=2021;volume=37;issue=2;spage=160;epage=170;aulast=Shahanesthetic drugsazithromycincovid-19dexamethasonefavipiravirhydroxychloroquineivermectinnitazoxanideremdesivirritonavirtocilizumab
spellingShingle Shagun B Shah
Uma Hariharan
Rajiv Chawla
Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents
Journal of Anaesthesiology Clinical Pharmacology
anesthetic drugs
azithromycin
covid-19
dexamethasone
favipiravir
hydroxychloroquine
ivermectin
nitazoxanide
remdesivir
ritonavir
tocilizumab
title Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents
title_full Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents
title_fullStr Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents
title_full_unstemmed Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents
title_short Common anti-COVID-19 drugs and their anticipated interaction with anesthetic agents
title_sort common anti covid 19 drugs and their anticipated interaction with anesthetic agents
topic anesthetic drugs
azithromycin
covid-19
dexamethasone
favipiravir
hydroxychloroquine
ivermectin
nitazoxanide
remdesivir
ritonavir
tocilizumab
url http://www.joacp.org/article.asp?issn=0970-9185;year=2021;volume=37;issue=2;spage=160;epage=170;aulast=Shah
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