Leveraging eQTLs to identify individual-level tissue of interest for a complex trait.
Genetic predisposition for complex traits often acts through multiple tissues at different time points during development. As a simple example, the genetic predisposition for obesity could be manifested either through inherited variants that control metabolism through regulation of genes expressed i...
| Hlavní autoři: | , , , , , , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2021-05-01
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| Edice: | PLoS Computational Biology |
| On-line přístup: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008915&type=printable |