The cytoprotective effect of different doses of Sildenafil on indomethacin-induced gastric mucosal damage in rats:
Background: Sildenafil, a selective phosphodiesterase -5 (PDE-5) inhibitor increases cyclic guanosine monophosphate (cGMP) and amplifies many biological actions of nitric oxide (NO) which is an important mediator of gastric mucosal defense ; was evaluated in this study using different doses for its...
Main Authors: | Samir Y. N. Matloub, Mohammed J. Manna |
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Format: | Article |
Language: | English |
Published: |
College of Medicine University of Baghdad
2011-01-01
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Series: | مجلة كلية الطب |
Subjects: | |
Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/950 |
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