Macrophages drive KSHV B cell latency

Macrophages drive KSHV B cell latency

Summary: Kaposi’s sarcoma herpesvirus (KSHV) establishes lifelong infection and persists in latently infected B cells. Paradoxically, in vitro B cell infection is inefficient, and cells rapidly die, suggesting the absence of necessary factor(s). KSHV epidemiology unexpectedly mirrors that of malaria...

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Bibliographic Details
Main Authors: Agnieszka Szymula, Gabriela Samayoa-Reyes, Sidney Ogolla, Bing Liu, Shijun Li, Athira George, Nicholas Van Sciver, Rosemary Rochford, J. Pedro Simas, Kenneth M. Kaye
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723007787

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